Transition State Structure for ADP-Ribosylation of Eukaryotic Elongation Factor 2 Catalyzed by Diphtheria Toxin

Chemical Compounds

• Transition State Structure 82%
• Kinetic Isotope Effect 71%
• Toxin 62%
• Bond Order 59%
• Isotope Effect 53%
• Nicotinamide 42%
• Ribosylation 41%
• Transition State 32%
• Diphthamide Residue 27%
• ADP 27%
• Diphthamide 24%
• Nucleophile 22%
• Exotoxin 20%
• Poison 15%
• Ribose 14%
• Isotope 11%
• Catalysis 8%
• Density Functional Theory 8%
• Protein 5%
• Reaction Yield 5%
• Ion 5%

Medicine & Life Sciences

• Peptide Elongation Factor 2 100%
• Diphtheria Toxin 90%
• ADP-Ribosylation 89%
• Isotopes 70%
• NAD 33%
• diphthamide 24%
• Niacinamide 24%
• Kinetics 23%
• Density Functional Theory 11%
• Bacterial Toxins 8%
• Exotoxins 8%
• Ribose 8%
• imidazole 8%
• Intrinsic Factor 8%
• Bacterial Proteins 7%
• Catalysis 7%
• Cholera Toxin 7%
• Lethal Dose 50 7%
• Pertussis Toxin 7%
• Adenosine Diphosphate 6%
• Ions 5%
• Yeasts 5%
• Poisons 4%