TY - JOUR
T1 - Transient worsening of optic neuropathy as a sequela of the jarisch-herxheimer reaction in the treatment of lyme disease
AU - Strominger, Mitchell B.
AU - Slamovits, Thomas L.
AU - Herskovitz, Steven
AU - Lipton, Richard B.
PY - 1994/6
Y1 - 1994/6
N2 - A 58-year-old woman developed neurologic and neuro-ophthalmologic manifestations of Lyme disease, including a radiculomyelitis, cranial neuritis and mild right optic neuropathy. Upon treatment with intravenous ceftriaxone a Jarisch-Herxheimer reaction occurred with encephalopathy, mild fever, worsening radiculomyelitis, and deterioration of her visual acuity. Intravenous methyl-prednisolone was given, and the visual acuity recovered over 72 hours. This case suggests that transient worsening of optic neuropathy can develop as a sequela of the Jarisch-Herxheimer reaction in the treatment of Lyme disease.
AB - A 58-year-old woman developed neurologic and neuro-ophthalmologic manifestations of Lyme disease, including a radiculomyelitis, cranial neuritis and mild right optic neuropathy. Upon treatment with intravenous ceftriaxone a Jarisch-Herxheimer reaction occurred with encephalopathy, mild fever, worsening radiculomyelitis, and deterioration of her visual acuity. Intravenous methyl-prednisolone was given, and the visual acuity recovered over 72 hours. This case suggests that transient worsening of optic neuropathy can develop as a sequela of the Jarisch-Herxheimer reaction in the treatment of Lyme disease.
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U2 - 10.1097/00041327-199406000-00004
DO - 10.1097/00041327-199406000-00004
M3 - Article
C2 - 7951931
AN - SCOPUS:0027980693
SN - 1070-8022
VL - 14
SP - 77
EP - 80
JO - Journal of Neuro-Ophthalmology
JF - Journal of Neuro-Ophthalmology
IS - 2
ER -