TY - JOUR
T1 - Transient hypothyroxinemia of prematurity
AU - La Gamma, Edmund F.
AU - Korzeniewski, Steven J.
AU - Ballabh, Praveen
AU - Paneth, Nigel
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Thyroid hormones play an important role in central nervous system development, starting from the exclusive maternal contribution in the first trimester and transitioning to a fully independent servo-control system at term birth. Extremely preterm delivery before 28 weeks’ gestational age disrupts this normal transition and reveals the challenge of whether replacement hormone will benefit cognitive and motor development. Although the evidence regarding deficiency is compelling, the hormone replacement question remains unanswered for preterm neonates.
AB - Thyroid hormones play an important role in central nervous system development, starting from the exclusive maternal contribution in the first trimester and transitioning to a fully independent servo-control system at term birth. Extremely preterm delivery before 28 weeks’ gestational age disrupts this normal transition and reveals the challenge of whether replacement hormone will benefit cognitive and motor development. Although the evidence regarding deficiency is compelling, the hormone replacement question remains unanswered for preterm neonates.
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U2 - 10.1542/neo.17-7-e394
DO - 10.1542/neo.17-7-e394
M3 - Article
AN - SCOPUS:84977546052
SN - 0191-9601
VL - 17
SP - e394-e402
JO - Pediatrics in Review
JF - Pediatrics in Review
IS - 7
ER -