Transient exercise-induced water intoxication and rhabdomyolysis

Chaim Putterman, L. Levy, D. Rubinger

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Water loading only rarely results in adverse effects due to the high efficiency of the kidney in excreting free water. However, when renal diluting ability is impaired, such as in inappropriate vasopressin secretion, water intoxication can occur in otherwise normal individuals. We report the case of a 19-year-old man with acute voluntary water intoxication following exercise, which resulted in a transient defect in renal diluting capability. Hyponatremia was further complicated rhabdomyolysis. We review the literature regarding other cases of hyponatremia following excessive water intake, and discuss the possible association between hyponatremia and rhabdomyolysis. We conclude that monitoring of muscle enzymes is indicated in acute hyponatremia, to allow for timely intervention intended to prevent rhabdomyolysis-associated acute renal failure.

Original languageEnglish (US)
Pages (from-to)206-209
Number of pages4
JournalAmerican Journal of Kidney Diseases
Volume21
Issue number2
StatePublished - 1993
Externally publishedYes

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Water Intoxication
Rhabdomyolysis
Hyponatremia
Exercise
Kidney
Water
Vasopressins
Acute Kidney Injury
Drinking
Muscles
Enzymes

ASJC Scopus subject areas

  • Nephrology

Cite this

Transient exercise-induced water intoxication and rhabdomyolysis. / Putterman, Chaim; Levy, L.; Rubinger, D.

In: American Journal of Kidney Diseases, Vol. 21, No. 2, 1993, p. 206-209.

Research output: Contribution to journalArticle

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