Abstract
Ludwig et al. chart the dynamic transcriptional and chromatin landscapes as hematopoietic stem and progenitor cells differentiate into mature red blood cells. This multi-omic profiling reveals dynamic transcription factor activities and human genetic variation that modulate this process.
Original language | English (US) |
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Pages (from-to) | 3228-3240.e7 |
Journal | Cell Reports |
Volume | 27 |
Issue number | 11 |
DOIs | |
State | Published - Jun 11 2019 |
Externally published | Yes |
Keywords
- GWAS
- chromatin accessibility
- erythropoiesis
- hematopoiesis
- human genetics
- red blood cell
- transcriptomics
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology