Transcriptional profiling of whole blood: A rich source of immune biomarkers in cancer

Y. Saenger, E. de Moll, Y. Fu

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Immunotherapy is at the forefront of cancer treatment, and biomarkers are urgently needed to predict patient response to therapy. Recently, we discovered a 4-gene peripheral blood mRNA signature for prolonged survival in patients treated with tremelimumab. Peripheral blood mRNA is a readily accessible and under-utilized source of clinically relevant biomarkers.

Original languageEnglish (US)
Article numbere944056
JournalOncoImmunology
Volume3
Issue number7
DOIs
StatePublished - 2014
Externally publishedYes

Keywords

  • Biomarker
  • Immunotherapy
  • mRNA
  • Peripheral blood
  • Tremelimumab

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Oncology

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