Transcatheter Therapies for Treating Tricuspid Regurgitation

Josep Rodés-Cabau, Rebecca T. Hahn, Azeem Latib, Michael Laule, Alexander Lauten, Francesco Maisano, Joachim Schofer, Francisco Campelo-Parada, Rishi Puri, Alec Vahanian

Research output: Contribution to journalReview articlepeer-review

142 Scopus citations

Abstract

Tricuspid valve (TV) disease has been relatively neglected, despite the known association between severe tricuspid regurgitation (TR) and mortality. Few patients undergo isolated tricuspid surgery, which remains associated with high in-hospital mortality rates, particularly in patients with prior left-sided valve surgery. Patients with severe TR are often managed medically for years before TV repair or replacement. Current guidelines recommend TV repair in the presence of a dilated tricuspid annulus at the time of a left-sided valve surgical intervention, even if regurgitation is mild. This proposed algorithm aims to prevent the inevitable progression to severe TR and the need for a second surgical intervention. Recently, novel transcatheter treatment options were developed for treating patients with severe TR and right heart failure with prohibitive surgical risk. Here we describe currently available transcatheter treatment options for severe TR implanted at different levels: the junction between vena cavae and right atrium; the tricuspid annulus; or between TV leaflets, improving coaptation.

Original languageEnglish (US)
Pages (from-to)1829-1845
Number of pages17
JournalJournal of the American College of Cardiology
Volume67
Issue number15
DOIs
StatePublished - Apr 19 2016
Externally publishedYes

Keywords

  • cardiac catheterization
  • echocardiography
  • pulmonary hypertension
  • right ventricular dysfunction
  • tricuspid valve
  • tricuspid valve insufficiency

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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