Transcatheter aortic valve implantation: Current status and future perspectives

T. J. Cahill, M. Chen, K. Hayashida, A. Latib, T. Modine, N. Piazza, S. Redwood, L. Søndergaard, B. D. Prendergast

Research output: Contribution to journalReview articlepeer-review

83 Scopus citations

Abstract

In the 16 years since the first pioneering procedure, transcatheter aortic valve implantation (TAVI) has come of age and become a routine strategy for aortic valve replacement, increasingly performed under conscious sedation via transfemoral access. Simplification of the procedure, accumulation of clinical experience, and improvements in valve design and delivery systems have led to a dramatic reduction in complication rates. These advances have allowed transition to lower risk populations, and outcome data from the PARTNER 2A and SURTAVI trials have established a clear evidence base for use in intermediate risk patients. Ongoing studies with an expanding portfolio of devices seem destined to expand indications for TAVI towards lower risk, younger and asymptomatic populations. In this article, we outline recent advances, new devices and current guidelines informing the use of TAVI, and describe remaining uncertainties that need to be addressed.

Original languageEnglish (US)
Pages (from-to)2625-2634
Number of pages10
JournalEuropean heart journal
Volume39
Issue number28
DOIs
StatePublished - Jul 21 2018
Externally publishedYes

Keywords

  • Aortic stenosis
  • Aortic valve replacement
  • Computed tomography
  • TAVI
  • TAVR
  • Transcatheter aortic valve implantation
  • Transcatheter aortic valve replacement

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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