Toward a better understanding of pharmacokinetics of nanomaterials

Chengke Zhang; Qiu Zhang; Yi Zhang; Bing Yan

doi:10.2174/1381612811319370010

Toward a better understanding of pharmacokinetics of nanomaterials

Chengke Zhang, Qiu Zhang, Yi Zhang, Bing Yan

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Nanotechnology has promising applications in biomedicine, such as in drug delivery, diagnosis, and tissue engineering. The pharmacokinetics of nanomaterials significantly affects their biological behavior in vivo, affecting their biomedical applications and potential nanotoxicity. In this review, we highlight some recent advances in the pharmacokinetic studies of representative nanomaterials. We focus on the relationships between the physicochemical properties of nanomaterials and physiological consequences.

Original language	English (US)
Pages (from-to)	6667-6680
Number of pages	14
Journal	Current pharmaceutical design
Volume	19
Issue number	37
DOIs	https://doi.org/10.2174/1381612811319370010
State	Published - 2013
Externally published	Yes

Keywords

Absorption
Distribution
Excretion
Metabolism
Nanomaterials
Pharmacokinetics

ASJC Scopus subject areas

Pharmacology
Drug Discovery

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10.2174/1381612811319370010

Cite this

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title = "Toward a better understanding of pharmacokinetics of nanomaterials",

abstract = "Nanotechnology has promising applications in biomedicine, such as in drug delivery, diagnosis, and tissue engineering. The pharmacokinetics of nanomaterials significantly affects their biological behavior in vivo, affecting their biomedical applications and potential nanotoxicity. In this review, we highlight some recent advances in the pharmacokinetic studies of representative nanomaterials. We focus on the relationships between the physicochemical properties of nanomaterials and physiological consequences.",

keywords = "Absorption, Distribution, Excretion, Metabolism, Nanomaterials, Pharmacokinetics",

author = "Chengke Zhang and Qiu Zhang and Yi Zhang and Bing Yan",

year = "2013",

doi = "10.2174/1381612811319370010",

language = "English (US)",

volume = "19",

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journal = "Current pharmaceutical design",

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TY - JOUR

T1 - Toward a better understanding of pharmacokinetics of nanomaterials

AU - Zhang, Chengke

AU - Zhang, Qiu

AU - Zhang, Yi

AU - Yan, Bing

PY - 2013

Y1 - 2013

N2 - Nanotechnology has promising applications in biomedicine, such as in drug delivery, diagnosis, and tissue engineering. The pharmacokinetics of nanomaterials significantly affects their biological behavior in vivo, affecting their biomedical applications and potential nanotoxicity. In this review, we highlight some recent advances in the pharmacokinetic studies of representative nanomaterials. We focus on the relationships between the physicochemical properties of nanomaterials and physiological consequences.

AB - Nanotechnology has promising applications in biomedicine, such as in drug delivery, diagnosis, and tissue engineering. The pharmacokinetics of nanomaterials significantly affects their biological behavior in vivo, affecting their biomedical applications and potential nanotoxicity. In this review, we highlight some recent advances in the pharmacokinetic studies of representative nanomaterials. We focus on the relationships between the physicochemical properties of nanomaterials and physiological consequences.

KW - Absorption

KW - Distribution

KW - Excretion

KW - Metabolism

KW - Nanomaterials

KW - Pharmacokinetics

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UR - http://www.scopus.com/inward/citedby.url?scp=84887923610&partnerID=8YFLogxK

U2 - 10.2174/1381612811319370010

DO - 10.2174/1381612811319370010

M3 - Review article

C2 - 23621528

AN - SCOPUS:84887923610

SN - 1381-6128

VL - 19

SP - 6667

EP - 6680

JO - Current pharmaceutical design

JF - Current pharmaceutical design

IS - 37

ER -

Toward a better understanding of pharmacokinetics of nanomaterials

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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