Topography and intracranial sources of somatosensory evoked potentials in the monkey. II. Cortical components

Research output: Contribution to journalArticle

134 Citations (Scopus)

Abstract

Averaged somatosensory evoked potentials (SEPs) and associated multiple unit activity (MUA) were recorded from a series of epidural and intracortical locations following stimulation of the contralateral median nerve in the monkey. Cortical components were differentiated from the earlier subcortical activity and the intracerebral distribution and sources of each cortical potential were determined. Under barbiturate anesthesia the SEP wave form is simplified and can be wholly attributed to two sources. The earliest cortical activity consists of a biphasic P10-N20 wave which is generated in the posterior bank of the central sulcus. A second wave form, P12-N25, originates in the crown of the postcentral gyrus. No other cortical areas are active. In the alert state the morphology of the surface SEP is complex and reflects the interaction of volume conducted activity from several adjacent cortical sources. The wave form overlying the hand area of the postcentral gyrus consists of P12, P20, P40, N25 and P110. Precentral recordings exhibit P10, P13, N13, N20, P24, N45 and P110. Six anatomical sources have been identified. P10 and N20 originate in the posterior bank of the central sulcus including areas 3a and 3b and are volume conducted in an anteroposterior direction. P12 originates in area 1 as well as the anterior portion of area 2. P20 is generated in the medial portion of the postcentral gyrus including area 5. The source of P40 lies within the lateral portion of the parietal lobe including area 7b. Two components were generated in precentral cortex: P13/N13 originates principally in area 4 within the anterior bank of the central sulcus and P24 reflects activity in the anteromedial portion of the precentral gyrus including area 6. The long latency SEP components, N45 and P110, are generated widely within the somesthetic areas of postcentral cortex. The early cortical SEP components recorded in the monkey closely resemble in configuration and topography those recorded from man although the latter are longer in latency, reflecting interspecies differences in the length of conduction pathways as well as in cortical processing time.

Original languageEnglish (US)
Pages (from-to)1-18
Number of pages18
JournalElectroencephalography and Clinical Neurophysiology
Volume51
Issue number1
DOIs
StatePublished - 1981

Fingerprint

Somatosensory Evoked Potentials
Haplorhini
Somatosensory Cortex
Parietal Lobe
Median Nerve
Frontal Lobe
Crowns
Anesthesia
Hand

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

@article{d4bb375159e84f50b01ccc164dde4792,
title = "Topography and intracranial sources of somatosensory evoked potentials in the monkey. II. Cortical components",
abstract = "Averaged somatosensory evoked potentials (SEPs) and associated multiple unit activity (MUA) were recorded from a series of epidural and intracortical locations following stimulation of the contralateral median nerve in the monkey. Cortical components were differentiated from the earlier subcortical activity and the intracerebral distribution and sources of each cortical potential were determined. Under barbiturate anesthesia the SEP wave form is simplified and can be wholly attributed to two sources. The earliest cortical activity consists of a biphasic P10-N20 wave which is generated in the posterior bank of the central sulcus. A second wave form, P12-N25, originates in the crown of the postcentral gyrus. No other cortical areas are active. In the alert state the morphology of the surface SEP is complex and reflects the interaction of volume conducted activity from several adjacent cortical sources. The wave form overlying the hand area of the postcentral gyrus consists of P12, P20, P40, N25 and P110. Precentral recordings exhibit P10, P13, N13, N20, P24, N45 and P110. Six anatomical sources have been identified. P10 and N20 originate in the posterior bank of the central sulcus including areas 3a and 3b and are volume conducted in an anteroposterior direction. P12 originates in area 1 as well as the anterior portion of area 2. P20 is generated in the medial portion of the postcentral gyrus including area 5. The source of P40 lies within the lateral portion of the parietal lobe including area 7b. Two components were generated in precentral cortex: P13/N13 originates principally in area 4 within the anterior bank of the central sulcus and P24 reflects activity in the anteromedial portion of the precentral gyrus including area 6. The long latency SEP components, N45 and P110, are generated widely within the somesthetic areas of postcentral cortex. The early cortical SEP components recorded in the monkey closely resemble in configuration and topography those recorded from man although the latter are longer in latency, reflecting interspecies differences in the length of conduction pathways as well as in cortical processing time.",
author = "Arezzo, {Joseph C.} and Vaughan, {H. G.} and Legatt, {Alan D.}",
year = "1981",
doi = "10.1016/0013-4694(81)91505-4",
language = "English (US)",
volume = "51",
pages = "1--18",
journal = "Electroencephalography and Clinical Neurophysiology",
issn = "0013-4694",
publisher = "Elsevier BV",
number = "1",

}

TY - JOUR

T1 - Topography and intracranial sources of somatosensory evoked potentials in the monkey. II. Cortical components

AU - Arezzo, Joseph C.

AU - Vaughan, H. G.

AU - Legatt, Alan D.

PY - 1981

Y1 - 1981

N2 - Averaged somatosensory evoked potentials (SEPs) and associated multiple unit activity (MUA) were recorded from a series of epidural and intracortical locations following stimulation of the contralateral median nerve in the monkey. Cortical components were differentiated from the earlier subcortical activity and the intracerebral distribution and sources of each cortical potential were determined. Under barbiturate anesthesia the SEP wave form is simplified and can be wholly attributed to two sources. The earliest cortical activity consists of a biphasic P10-N20 wave which is generated in the posterior bank of the central sulcus. A second wave form, P12-N25, originates in the crown of the postcentral gyrus. No other cortical areas are active. In the alert state the morphology of the surface SEP is complex and reflects the interaction of volume conducted activity from several adjacent cortical sources. The wave form overlying the hand area of the postcentral gyrus consists of P12, P20, P40, N25 and P110. Precentral recordings exhibit P10, P13, N13, N20, P24, N45 and P110. Six anatomical sources have been identified. P10 and N20 originate in the posterior bank of the central sulcus including areas 3a and 3b and are volume conducted in an anteroposterior direction. P12 originates in area 1 as well as the anterior portion of area 2. P20 is generated in the medial portion of the postcentral gyrus including area 5. The source of P40 lies within the lateral portion of the parietal lobe including area 7b. Two components were generated in precentral cortex: P13/N13 originates principally in area 4 within the anterior bank of the central sulcus and P24 reflects activity in the anteromedial portion of the precentral gyrus including area 6. The long latency SEP components, N45 and P110, are generated widely within the somesthetic areas of postcentral cortex. The early cortical SEP components recorded in the monkey closely resemble in configuration and topography those recorded from man although the latter are longer in latency, reflecting interspecies differences in the length of conduction pathways as well as in cortical processing time.

AB - Averaged somatosensory evoked potentials (SEPs) and associated multiple unit activity (MUA) were recorded from a series of epidural and intracortical locations following stimulation of the contralateral median nerve in the monkey. Cortical components were differentiated from the earlier subcortical activity and the intracerebral distribution and sources of each cortical potential were determined. Under barbiturate anesthesia the SEP wave form is simplified and can be wholly attributed to two sources. The earliest cortical activity consists of a biphasic P10-N20 wave which is generated in the posterior bank of the central sulcus. A second wave form, P12-N25, originates in the crown of the postcentral gyrus. No other cortical areas are active. In the alert state the morphology of the surface SEP is complex and reflects the interaction of volume conducted activity from several adjacent cortical sources. The wave form overlying the hand area of the postcentral gyrus consists of P12, P20, P40, N25 and P110. Precentral recordings exhibit P10, P13, N13, N20, P24, N45 and P110. Six anatomical sources have been identified. P10 and N20 originate in the posterior bank of the central sulcus including areas 3a and 3b and are volume conducted in an anteroposterior direction. P12 originates in area 1 as well as the anterior portion of area 2. P20 is generated in the medial portion of the postcentral gyrus including area 5. The source of P40 lies within the lateral portion of the parietal lobe including area 7b. Two components were generated in precentral cortex: P13/N13 originates principally in area 4 within the anterior bank of the central sulcus and P24 reflects activity in the anteromedial portion of the precentral gyrus including area 6. The long latency SEP components, N45 and P110, are generated widely within the somesthetic areas of postcentral cortex. The early cortical SEP components recorded in the monkey closely resemble in configuration and topography those recorded from man although the latter are longer in latency, reflecting interspecies differences in the length of conduction pathways as well as in cortical processing time.

UR - http://www.scopus.com/inward/record.url?scp=0019400017&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019400017&partnerID=8YFLogxK

U2 - 10.1016/0013-4694(81)91505-4

DO - 10.1016/0013-4694(81)91505-4

M3 - Article

C2 - 6161773

AN - SCOPUS:0019400017

VL - 51

SP - 1

EP - 18

JO - Electroencephalography and Clinical Neurophysiology

JF - Electroencephalography and Clinical Neurophysiology

SN - 0013-4694

IS - 1

ER -