How Does Gravity Influence the Distribution of Lordosis in Patients With Sagittal Malalignment?

Study Design: Retrospective cohort study. Objective: Compare the supine vs standing radiographs of patients with adult spinal deformity against ideals defined by healthy standing alignment. Methods: 56 patients with primary sagittal ASD (SRS-Schwab Type N) and 119 asymptomatic volunteers were included. Standing alignment of asymptomatic volunteers was used to calculate PI-based formulas for normative age-adjusted standing PI–LL, L4–S1, and L1–L4. These formulas were applied to the supine and standing alignment of ASD cohort. Analyses were repeated on a cohort of 25 patients with at least 5 degrees of lumbar flexibility (difference between supine and standing lordosis). Results: The asymptomatic cohort yielded the following PI-based formulas: PI–LL = −38.3 +.41*PI +.21*Age, L4–S1 = 45.3–.18*Age, L1–L4 = −3 +.48*PI). PI–LL improved with supine positioning (mean 8.9 ± 18.7°, P <.001), though not enough to correct to age-matched norms (mean offset 12.2 ± 16.9°). Compared with mean normative alignment at L1–L4 (22.1 ± 6.2°), L1–L4 was flatter on standing (7.2 ± 17.0°, P <.001) and supine imaging (8.5 ± 15.0°, P <.001). L4-S1 lordosis of subjects with L1-S1 flexibility >5° corrected on supine imaging (33.9 ± 11.1°, P = 1.000), but L1–L4 did not (23.0 ± 6.2° norm vs 2.2 ± 14.4° standing, P <.001; vs 7.3 ± 12.9° supine, P <.001). Conclusions: When the effects of gravity are removed, the distal portion of the lumbar spine (i.e., below the apex of lordosis) corrects, suggesting that structural lumbar deformity is primarily proximal.