Timing and predictors of early urologic and infectious complications after renal transplant: An analysis of a New York statewide database

Wilson Sui, Michael J. Lipsky, Justin T. Matulay, Dennis J. Robins, Ifeanyi C. Onyeji, Maxwell B. James, Marissa C. Theofanides, Sven Wenske

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Objectives: The most common complications after renal transplant are urologic and are a cause of significant morbidity in a vulnerable population. We sought to characterize the timing and predictors of urologic complications after renal transplant using a statewide database. Materials and Methods: We queried the New York Statewide Planning and Research Cooperative System database to identify patients who underwent renal transplant from 2005 to 2013. Postoperative com - plications included hydronephrosis, ureteral stricture, vesicoureteral reflux, nephrolithiasis, and urinary tract infections. Cox proportional hazards model was used to assess independent predictors of urologic com - plications. Results: In total, 9038 patients were included in the analyses. Urologic complications occurred in 11.3% of patients and included hydronephrosis (12.0%), nephrolithiasis (2.8%), ureteral stricture (2.4%), and vesicoureteral reflux (1.5%). We found that 23% experienced at least one urinary tract infection. On multivariate analysis, predictors of urologic com - plications included medicare insurance, hypertension, and prior urinary tract infection. Graft recipients from living donors were less likely to experience urologic complications than deceased-donor kidney recipients (P <.001). Conclusions: Urologic complications occur in a significant proportion of renal transplants. Further study is needed to identify risk factors for com - plications after renal transplantation to decrease morbidity in this vulnerable population.

Original languageEnglish (US)
Pages (from-to)665-670
Number of pages6
JournalExperimental and Clinical Transplantation
Volume16
Issue number6
DOIs
StatePublished - Dec 2018
Externally publishedYes

Keywords

  • Hydronephrosis
  • Kidney
  • Nephrolithiasis
  • Transplantation
  • Urinary tract infections
  • Vesicoureteral reflux

ASJC Scopus subject areas

  • Transplantation

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