TY - JOUR
T1 - Timing and predictors of early urologic and infectious complications after renal transplant
T2 - An analysis of a New York statewide database
AU - Sui, Wilson
AU - Lipsky, Michael J.
AU - Matulay, Justin T.
AU - Robins, Dennis J.
AU - Onyeji, Ifeanyi C.
AU - James, Maxwell B.
AU - Theofanides, Marissa C.
AU - Wenske, Sven
N1 - Publisher Copyright:
© Başkent University 2018.
PY - 2018/12
Y1 - 2018/12
N2 - Objectives: The most common complications after renal transplant are urologic and are a cause of significant morbidity in a vulnerable population. We sought to characterize the timing and predictors of urologic complications after renal transplant using a statewide database. Materials and Methods: We queried the New York Statewide Planning and Research Cooperative System database to identify patients who underwent renal transplant from 2005 to 2013. Postoperative com - plications included hydronephrosis, ureteral stricture, vesicoureteral reflux, nephrolithiasis, and urinary tract infections. Cox proportional hazards model was used to assess independent predictors of urologic com - plications. Results: In total, 9038 patients were included in the analyses. Urologic complications occurred in 11.3% of patients and included hydronephrosis (12.0%), nephrolithiasis (2.8%), ureteral stricture (2.4%), and vesicoureteral reflux (1.5%). We found that 23% experienced at least one urinary tract infection. On multivariate analysis, predictors of urologic com - plications included medicare insurance, hypertension, and prior urinary tract infection. Graft recipients from living donors were less likely to experience urologic complications than deceased-donor kidney recipients (P <.001). Conclusions: Urologic complications occur in a significant proportion of renal transplants. Further study is needed to identify risk factors for com - plications after renal transplantation to decrease morbidity in this vulnerable population.
AB - Objectives: The most common complications after renal transplant are urologic and are a cause of significant morbidity in a vulnerable population. We sought to characterize the timing and predictors of urologic complications after renal transplant using a statewide database. Materials and Methods: We queried the New York Statewide Planning and Research Cooperative System database to identify patients who underwent renal transplant from 2005 to 2013. Postoperative com - plications included hydronephrosis, ureteral stricture, vesicoureteral reflux, nephrolithiasis, and urinary tract infections. Cox proportional hazards model was used to assess independent predictors of urologic com - plications. Results: In total, 9038 patients were included in the analyses. Urologic complications occurred in 11.3% of patients and included hydronephrosis (12.0%), nephrolithiasis (2.8%), ureteral stricture (2.4%), and vesicoureteral reflux (1.5%). We found that 23% experienced at least one urinary tract infection. On multivariate analysis, predictors of urologic com - plications included medicare insurance, hypertension, and prior urinary tract infection. Graft recipients from living donors were less likely to experience urologic complications than deceased-donor kidney recipients (P <.001). Conclusions: Urologic complications occur in a significant proportion of renal transplants. Further study is needed to identify risk factors for com - plications after renal transplantation to decrease morbidity in this vulnerable population.
KW - Hydronephrosis
KW - Kidney
KW - Nephrolithiasis
KW - Transplantation
KW - Urinary tract infections
KW - Vesicoureteral reflux
UR - http://www.scopus.com/inward/record.url?scp=85057281199&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85057281199&partnerID=8YFLogxK
U2 - 10.6002/ect.2016.0357
DO - 10.6002/ect.2016.0357
M3 - Article
C2 - 28697717
AN - SCOPUS:85057281199
SN - 1304-0855
VL - 16
SP - 665
EP - 670
JO - Experimental and Clinical Transplantation
JF - Experimental and Clinical Transplantation
IS - 6
ER -