Thyroid Storm Presenting as Psychosis

Dimpi Desai, Sara Zahedpour Anaraki, Neetha Reddy, Eric Epstein, Vafa Tabatabaie

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Thyroid storm is a life-threatening endocrine emergency with an incidence rate of 1% to 2%. It is a systemic condition of excessive thyroid hormone production and release leading to thermoregulatory, adrenergic, neuropsychiatric, cardiovascular, and abdominal manifestations. Although it is a rare condition, it carries a significant mortality rate. Hence, knowing the common and uncommon presentations of thyroid storm is important for its prompt diagnosis and treatment. In this article, we present an unusual case of a young woman who presented with psychosis as the manifesting symptom of thyroid storm. She did not respond adequately to conventional medical treatment, requiring plasmapheresis and a definitive thyroidectomy, which ultimately led to the return of patient’s baseline mental status and a dramatic recovery.

Original languageEnglish (US)
JournalJournal of Investigative Medicine High Impact Case Reports
StatePublished - May 16 2018


  • hyperthyroidism
  • plasmapheresis
  • psychosis
  • thyroid storm
  • thyrotoxicosis

ASJC Scopus subject areas

  • Epidemiology
  • Safety, Risk, Reliability and Quality
  • Safety Research


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