Thy-1 determinants are present on many murine hematopoietic cells other than T cells

R. S. Basch, Joan W. Berman

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

The development of a highly amplified immunofluorescence assay and the availability of monoclonal anti-Thy-1 antibodies have provided the methodology to reexamine the presence of Thy-1 antigen on murine lymphohematopoietic cells. The representation of this antigen is not, as previously believed, restricted to the T cell compartment of these cells. It is present on a significant number of mouse bone marrow cells (25-30%), including, as in the rat, multipotential stem cells, prothymocytes and some B cell precursors. Eosinophils and some immature myeloid cells are also antigen-positive.

Original languageEnglish (US)
Pages (from-to)359-364
Number of pages6
JournalEuropean Journal of Immunology
Volume12
Issue number5
StatePublished - 1982
Externally publishedYes

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Thy-1 Antigens
T-Lymphocytes
Antigens
B-Lymphoid Precursor Cells
Myeloid Cells
Eosinophils
Bone Marrow Cells
Fluorescent Antibody Technique
Stem Cells
anti-Thy antibody

ASJC Scopus subject areas

  • Immunology

Cite this

Thy-1 determinants are present on many murine hematopoietic cells other than T cells. / Basch, R. S.; Berman, Joan W.

In: European Journal of Immunology, Vol. 12, No. 5, 1982, p. 359-364.

Research output: Contribution to journalArticle

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