Thrombolytic-related complication in a case of misdiagnosed myocardial infarction

Osereme Irivbogbe, Brooks Mirrer, Pablo Loarte, Michael Gale, Ronny Cohen

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The importance of early thrombolysis in acute myocardial infarction has been highlighted in several large trials. The clinical decision is often taken by physicians who need to take a rapid action with the risk of misdiagnosing non-coronary events that mimic myocardial infarction. Here we describe a case of acute pericarditis in a 37-year-old man whom received thrombolysis and developed a sudden hemorrhagic pericardial effusion that evolved rapidly into a cardiac tamponade. These errors leading to lethal thrombolysis complications have been surprisingly rare; but a correct diagnosis of aortic dissection or hemorrhagic pericarditis needs to be stressed because even after obtaining the correct diagnosis, the prolonged disturbance of hemostasis prevents a rapid therapy being instigated.

Original languageEnglish (US)
Pages (from-to)83-87
Number of pages5
JournalAcute Cardiac Care
Issue number2
StatePublished - Jun 2014
Externally publishedYes


  • Myocardial infarction
  • Streptokinase
  • Thrombolysis

ASJC Scopus subject areas

  • Emergency Medicine
  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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