Thermodynamic studies of lectin-carbohydrate interactions by isothermal titration calorimetry

Tarun K. Dam, Curtis F. Brewer

Research output: Contribution to journalArticle

399 Citations (Scopus)

Abstract

The isothermal titration calorimetry (ITC) measurements became an important and widely used method for investigating the thermodynamics of carbohydrate-lectin interactions. Thus, no other method affords the ease of directly determining thermodynamic binding parameters without modifying the carbohydrates or proteins of interest. This paper summarizes a wide range of lectin binding studies investigated by ITC during the past decade.

Original languageEnglish (US)
Pages (from-to)387-429
Number of pages43
JournalChemical Reviews
Volume102
Issue number2
DOIs
StatePublished - Feb 2002

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Calorimetry
Titration
Lectins
Carbohydrates
Thermodynamics
Proteins

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Thermodynamic studies of lectin-carbohydrate interactions by isothermal titration calorimetry. / Dam, Tarun K.; Brewer, Curtis F.

In: Chemical Reviews, Vol. 102, No. 2, 02.2002, p. 387-429.

Research output: Contribution to journalArticle

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