TY - JOUR
T1 - Therapy of experimental babesiosis
AU - Rowin, K. S.
AU - Tanowitz, H. B.
AU - Wittner, M.
PY - 1982
Y1 - 1982
N2 - Babesia microti infections established in hamsters were treated successfully with clindamycin. Regimens that contained this drug consistently cleared the infection rapidly and without relapse once the drug was discontinued. Late in the course of the infection, the addition of quinine, through the oral but not parenteral route, to clindamycin therapy, was more effective than clindamycin alone. Both clindamycin and the combination of clindamycin and oral quinine are safe, effective treatment for life-threatening babesiosis.
AB - Babesia microti infections established in hamsters were treated successfully with clindamycin. Regimens that contained this drug consistently cleared the infection rapidly and without relapse once the drug was discontinued. Late in the course of the infection, the addition of quinine, through the oral but not parenteral route, to clindamycin therapy, was more effective than clindamycin alone. Both clindamycin and the combination of clindamycin and oral quinine are safe, effective treatment for life-threatening babesiosis.
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U2 - 10.7326/0003-4819-97-4-556
DO - 10.7326/0003-4819-97-4-556
M3 - Article
C2 - 7125412
AN - SCOPUS:0019932528
SN - 0003-4819
VL - 97
SP - 556
EP - 558
JO - Annals of internal medicine
JF - Annals of internal medicine
IS - 4
ER -