The voyage to healthy longevity: From experimental models to the ultimate goal

Amiela Globerson, Nir Barzilai

Research output: Contribution to journalArticle

Abstract

Understanding mechanisms underlying longevity, and endeavor towards the specific goals of alleviating frailty in old age, require a comprehensive approach that considers the various theoretical and experimental approaches, as well as compiling the data on humans. This logistic has underlined the program of the conference, and is reflected in the present special issue. Considerable volume of data now point to distinct genes that are associated with exceptional longevity in humans, as reflected from the articles in this volume. However, this symposium also highlighted non-genetic effects, including physical, mental and social activities, and elucidate the relevant underlying mechanisms. The symposium focused on understanding the basis of human longevity coupled to extended health-span and function into old age.

Original languageEnglish (US)
Pages (from-to)225-229
Number of pages5
JournalMechanisms of Ageing and Development
Volume126
Issue number2
DOIs
StatePublished - Feb 1 2005

Keywords

  • Apoptosis
  • Centenarian
  • Growth hormone
  • HDL
  • IGF-1
  • LDL
  • Lipids
  • Longevity genes
  • Neurodegeneration
  • Skeletal tissues aging
  • Stem cells

ASJC Scopus subject areas

  • Aging
  • Developmental Biology

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