The voyage to healthy longevity: From experimental models to the ultimate goal

Amiela Globerson; Nir Barzilai

doi:10.1016/j.mad.2004.08.013

The voyage to healthy longevity: From experimental models to the ultimate goal

Amiela Globerson, Nir Barzilai

Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Understanding mechanisms underlying longevity, and endeavor towards the specific goals of alleviating frailty in old age, require a comprehensive approach that considers the various theoretical and experimental approaches, as well as compiling the data on humans. This logistic has underlined the program of the conference, and is reflected in the present special issue. Considerable volume of data now point to distinct genes that are associated with exceptional longevity in humans, as reflected from the articles in this volume. However, this symposium also highlighted non-genetic effects, including physical, mental and social activities, and elucidate the relevant underlying mechanisms. The symposium focused on understanding the basis of human longevity coupled to extended health-span and function into old age.

Original language	English (US)
Pages (from-to)	225-229
Number of pages	5
Journal	Mechanisms of Ageing and Development
Volume	126
Issue number	2
DOIs	https://doi.org/10.1016/j.mad.2004.08.013
State	Published - Feb 2005

Keywords

Apoptosis
Centenarian
Growth hormone
HDL
IGF-1
LDL
Lipids
Longevity genes
Neurodegeneration
Skeletal tissues aging
Stem cells

ASJC Scopus subject areas

Aging
Developmental Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.mad.2004.08.013

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title = "The voyage to healthy longevity: From experimental models to the ultimate goal",

abstract = "Understanding mechanisms underlying longevity, and endeavor towards the specific goals of alleviating frailty in old age, require a comprehensive approach that considers the various theoretical and experimental approaches, as well as compiling the data on humans. This logistic has underlined the program of the conference, and is reflected in the present special issue. Considerable volume of data now point to distinct genes that are associated with exceptional longevity in humans, as reflected from the articles in this volume. However, this symposium also highlighted non-genetic effects, including physical, mental and social activities, and elucidate the relevant underlying mechanisms. The symposium focused on understanding the basis of human longevity coupled to extended health-span and function into old age.",

keywords = "Apoptosis, Centenarian, Growth hormone, HDL, IGF-1, LDL, Lipids, Longevity genes, Neurodegeneration, Skeletal tissues aging, Stem cells",

author = "Amiela Globerson and Nir Barzilai",

note = "Funding Information: Organization of the conference was in the framework of activities of the SHALOM and VARDA YORAN Institute for Human Genome Research at Tel Aviv University. We acknowledge the support by the Ellison Medical Foundation (to N. Barzilai). We greatly appreciate the valuable suggestions towards the scientific program of the conference, provided by George M. Martin. Thanks are due to the Dozor Foundation Visiting Professor Scholarship awarded to Professor Barzilai for a visit to the Faculty of Health Sciences at Ben Gurion University of the Negev. The visit had a significant role in the initial steps of preparation of this special issue. ",

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KW - Stem cells

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The voyage to healthy longevity: From experimental models to the ultimate goal

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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