The use of electrophysiology for the assessment of diabetic neuropathy

Joseph C. Arezzo

doi:10.1002/(SICI)1520-6769(199707)21:1<13::AID-NRC203>3.0.CO;2-P

The use of electrophysiology for the assessment of diabetic neuropathy

Joseph C. Arezzo

Neuroscience

Research output: Contribution to journal › Review article › peer-review

38 Scopus citations

Abstract

Whole nerve electrophysiology can provide a battery of objective, reliable and specific measures that are sensitive to the progression of diabetic symmetrical polyneuropathy (DSPN). However, under standard conditions, these measures index limited aspects of neural activity, and then only in large diameter, myelinated axons. Nerve conduction is not synonymous with 'nerve function.' Electrophysiologic measures can be influenced by a variety of factors with different time courses of action and with different sensitivities to manipulation. The value of whole nerve electrophysiology must be based on a firm appreciation of the strengths and limitations of the procedure.

Original language	English (US)
Pages (from-to)	13-23
Number of pages	11
Journal	Neuroscience Research Communications
Volume	21
Issue number	1
DOIs	https://doi.org/10.1002/(SICI)1520-6769(199707)21:1<13::AID-NRC203>3.0.CO;2-P
State	Published - Jan 1 1997

Keywords

Diabetes mellitus
Electrophysiology
Nerve conduction
Neuropathy
Review

ASJC Scopus subject areas

Neuroscience(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/(SICI)1520-6769(199707)21:1<13::AID-NRC203>3.0.CO;2-P

Cite this

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AB - Whole nerve electrophysiology can provide a battery of objective, reliable and specific measures that are sensitive to the progression of diabetic symmetrical polyneuropathy (DSPN). However, under standard conditions, these measures index limited aspects of neural activity, and then only in large diameter, myelinated axons. Nerve conduction is not synonymous with 'nerve function.' Electrophysiologic measures can be influenced by a variety of factors with different time courses of action and with different sensitivities to manipulation. The value of whole nerve electrophysiology must be based on a firm appreciation of the strengths and limitations of the procedure.

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The use of electrophysiology for the assessment of diabetic neuropathy

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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