The ultrastructure of the peritoneal membrane in chronically dialysed rats

K. Wieczorowska-Tobis, A. Polubińska, R. Brelińska, A. Breborowicz

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The model to estimate peritoneal function in chronically dialysed rats was previously presented by us. The aim of the paper is to report the findings obtained in electron microscopy of peritoneal biopsies from Wistar rats dialysed for 1 month with high glucose dialysis solution. In control animals, thin mesothelial cells were covered with microvilli. The submesothelial tissue was composed of sparse bundles of parallelly oriented collagen fibers with a few resting cells. In chronically dialysed rats, mesothelial cell layer was thicker and cells were fully packed with intracellular structures, mainly secretory granules with a homogeneous content. The submesothelial tissue was expanded due to the increased amount of collagen fibers, oedema and increased amount of submesothelial cells which were activated. The use of electron microscopy to study the peritoneum in dialysed rats is an excellent supplement to the chronic functional model of peritoneal dialysis in rats.

Original languageEnglish (US)
Pages (from-to)209-210
Number of pages2
JournalFolia Histochemica et Cytobiologica
Volume39
Issue number2
StatePublished - 2001
Externally publishedYes

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Membranes
Electron Microscopy
Collagen
Peritoneum
Dialysis Solutions
Secretory Vesicles
Peritoneal Dialysis
Microvilli
Wistar Rats
Edema
Biopsy
Glucose

Keywords

  • Dialysis
  • Peritoneum
  • Rat
  • Ultrastructure

ASJC Scopus subject areas

  • Anatomy
  • Cell Biology

Cite this

Wieczorowska-Tobis, K., Polubińska, A., Brelińska, R., & Breborowicz, A. (2001). The ultrastructure of the peritoneal membrane in chronically dialysed rats. Folia Histochemica et Cytobiologica, 39(2), 209-210.

The ultrastructure of the peritoneal membrane in chronically dialysed rats. / Wieczorowska-Tobis, K.; Polubińska, A.; Brelińska, R.; Breborowicz, A.

In: Folia Histochemica et Cytobiologica, Vol. 39, No. 2, 2001, p. 209-210.

Research output: Contribution to journalArticle

Wieczorowska-Tobis, K, Polubińska, A, Brelińska, R & Breborowicz, A 2001, 'The ultrastructure of the peritoneal membrane in chronically dialysed rats', Folia Histochemica et Cytobiologica, vol. 39, no. 2, pp. 209-210.
Wieczorowska-Tobis K, Polubińska A, Brelińska R, Breborowicz A. The ultrastructure of the peritoneal membrane in chronically dialysed rats. Folia Histochemica et Cytobiologica. 2001;39(2):209-210.
Wieczorowska-Tobis, K. ; Polubińska, A. ; Brelińska, R. ; Breborowicz, A. / The ultrastructure of the peritoneal membrane in chronically dialysed rats. In: Folia Histochemica et Cytobiologica. 2001 ; Vol. 39, No. 2. pp. 209-210.
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