@article{763d3b7112b04c0f96fc110b7d1e6f3d,
title = "The TB structural genomics consortium: A resource for Mycobacterium tuberculosis biology",
abstract = "The TB Structural Genomics Consortium is an organization devoted to encouraging, coordinating, and facilitating the determination and analysis of structures of proteins from Mycobacterium tuberculosis. The Consortium members hope to work together with other M. tuberculosis researchers to identify M. tuberculosis proteins for which structural information could provide important biological information, to analyze and interpret structures of M. tuberculosis proteins, and to work collaboratively to test ideas about M. tuberculosis protein function that are suggested by structure or related to structural information. This review describes the TB Structural Genomics Consortium and some of the proteins for which the Consortium is in the progress of determining three-dimensional structures.",
keywords = "Drug discovery, Mycobacterium tuberculosis, Protein structure, Structural genomics, X-ray crystallography",
author = "Terwilliger, {T. C.} and Park, {M. S.} and Waldo, {G. S.} and J. Berendzen and Hung, {L. W.} and Kim, {C. Y.} and Smith, {C. V.} and Sacchettini, {J. C.} and M. Bellinzoni and R. Bossi and {De Rossi}, E. and A. Mattevi and A. Milano and G. Riccardi and M. Rizzi and Roberts, {M. M.} and Coker, {A. R.} and G. Fossati and P. Mascagni and Coates, {A. R.M.} and Wood, {S. P.} and Goulding, {C. W.} and Apostol, {M. I.} and Anderson, {D. H.} and Gill, {H. S.} and Eisenberg, {D. S.} and B. Taneja and S. Mande and E. Pohl and V. Lamzin and P. Tucker and M. Wilmanns and C. Colovos and W. Meyer-Klaucke and Munro, {A. W.} and McLean, {K. J.} and Marshall, {K. R.} and D. Leys and Yang, {J. K.} and Yoon, {H. J.} and Lee, {B. I.} and Lee, {M. G.} and Kwak, {J. E.} and Han, {B. W.} and Lee, {J. Y.} and Baek, {S. H.} and Suh, {S. W.} and Komen, {M. M.} and Arcus, {V. L.} and Baker, {E. N.} and Lott, {J. S.} and W. Jacobs and T. Alber and B. Rupp",
note = "Funding Information: Work from the laboratory of Se Won Suh was supported by the Korea Ministry of Science and Technology (NRL-2001, grant no. M1-0104000132-01J000006210). Work from the laboratory of University of Pavia was supported by the Italian Ministry of University and Scientific and Technological Research (MURST, grant COFIN-1998, COFIN-2002) and by the European Union research project Quality of Life and Management of Living Resources (Contract No. QLK2-2000-01761). Work from many of the laboratories was supported by the NIH. The UCLA authors wish to acknowledge Mari Gingery, Duilio Cascio, Michael Sawaya and Cameron Mura for useful suggestions and discussion. The UCLA work has been supported by grants from the Department of Energy and the National Institutes of Health. The coordinates for Rv1886c, Rv2220, Rv1926c and Rv2878c have been deposited in the Protein Data Bank with the accession numbers 1FOP , 1HTO, 1LM1 and 1LU4, respectively. The SGHMS authors wish to thank Jon Cooper, Darren Thompson, Gerard Kleywegt and Peter Tormay for their help and advice, the Raymond Burton Medical Trust for a grant to A.R.M.C. and the Wellcome Trust for a grant to S.P.W. We would like to thank David Christie for originally suggesting this area of study at Auckland, Kerry Loomes for help and advice with lipase assays, the Auckland Medical Research Foundation for a project grant to V.A. and J.S.L, and the New Economy Research Fund and the Marsden Fund for project grants to E.N.B. ",
year = "2003",
doi = "10.1016/S1472-9792(03)00051-9",
language = "English (US)",
volume = "83",
pages = "223--249",
journal = "Tuberculosis",
issn = "1472-9792",
publisher = "Churchill Livingstone",
number = "4",
}
