The stearoyl-coenzyme a desaturase 1 is essential for virulence and membrane stress in candida parapsilosis through unsaturated fatty acid production

Medicine & Life Sciences

• Candida parapsilosis 94%
• Coenzymes 92%
• Unsaturated Fatty Acids 76%
• Virulence 62%
• Membranes 42%
• Yeasts 33%
• Macrophages 14%
• Essential Fatty Acids 13%
• Gene Deletion 11%
• Cellular Structures 10%
• Growth 10%
• Coculture Techniques 10%
• Agar 9%
• Saccharomyces cerevisiae 9%
• Fungi 9%
• Salts 8%
• Fatty Acids 8%
• Nitric Oxide 8%
• Cattle 8%
• Cell Survival 7%
• Acids 7%
• Cell Membrane 7%
• Temperature 7%
• Infections 4%
• Serum 4%

Agriculture & Biology

• Candida parapsilosis 100%
• stearoyl-CoA desaturase 90%
• unsaturated fatty acids 70%
• virulence 57%
• yeasts 27%
• cells 22%
• macrophages 18%
• animal pathogenic fungi 15%
• gene deletion 11%
• mice 11%
• essential fatty acids 11%
• fetal bovine serum 11%
• coculture 11%
• saturated fatty acids 9%
• blood flow 9%
• cell viability 9%
• nitric oxide 9%
• cell membranes 8%
• Saccharomyces cerevisiae 8%
• stress response 8%
• agar 7%
• salts 7%
• biosynthesis 6%
• acids 5%
• infection 5%
• temperature 4%