Abstract
Objective : To determine risk factors for acute kidney injury (AKI) in preterm infants as a function of time of onset. Study Design : In this 5 1/2-year, single-center, retrospective study, incidence and timing of AKI was determined using modified Acute Kidney Injury Network criteria. Characteristics of newborns with and without AKI were compared by chi square and t-tests. Logistic regression was used to examine risk factors for AKI as a function of time of onset and potential confounders.Result:AKI occurred in 30.3% of 357 neonates; 72.2% was stage 1. Gestational ages (GA), initial Cr, maternal magnesium and volume resuscitation were associated with early AKI (days 0 to 1). Volume resuscitation, umbilical arterial line and receipt of non-steroidal anti-inflammatory drug (NSAID) for patent ductus arteriosus were associated with intermediate AKI (days 2 to 5). GA, steroids for early hypotension, necrotizing enterocolitis and sepsis were associated with late AKI (≥day 6). Conclusion : Stage 1 AKI is a common morbidity in our population. Risk factors for AKI in our population differed with time of onset.
Original language | English (US) |
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Pages (from-to) | 474-480 |
Number of pages | 7 |
Journal | Journal of Perinatology |
Volume | 36 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1 2016 |
Externally published | Yes |
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Obstetrics and Gynecology