The SILK flow diverter in the treatment of intracranial aneurysms

Santosh B. Murthy, Shreyansh Shah, Aditi Shastri, Chethan P. Venkatasubba Rao, Eric M. Bershad, Jose I. Suarez

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The SILK flow diverter (SFD; Balt Extrusion, Montmorency, France) is a flow diverting stent used in the endovascular treatment of intracranial aneurysms. It works on the principle of redirecting flow away from the aneurysm sac, leading to occlusion over time. We present a systematic review on the clinical outcomes and complications of the SFD. A literature search for English language articles were conducted on PubMed, Medline and EMBASE for articles on the treatment of intracranial aneurysms with the SILK flow diverter. The inclusion criteria were n > 10, use of SFD only, data on complications and aneurysm occlusion rate (AOR). Eight studies with 285 patients and 317 intracranial aneurysms were included. The mean age was 52.7 years and nearly 80% were women. In terms of angiographic distribution, 86.8% of aneurysms were located in the anterior circulation and 13.2% in the posterior circulation. As for the aneurysm size, 37.9% were classed as small, 44.4% as large and 17.7% as giant. Ischemic complications and parent artery occlusion each occurred in 10% of patients. Aneurysm rupture rate was 3.5%, while the cumulative mortality was 4.9%. The main outcome measure, 12 month AOR, was 81.8% with complete occlusion in 216 out of 264 aneurysms. Use of flow diverters for the treatment of intracranial aneurysm with complex morphologies has gained in popularity over the last few years. Our review suggests that SFD achieves comparable AOR to its contemporary, the Pipeline Embolization Device (ev3 Endovascular, Plymouth, MN, USA) but has a higher rate of higher rate of ischemic complications, aneurysm rupture and mortality.

Original languageEnglish (US)
Pages (from-to)203-206
Number of pages4
JournalJournal of Clinical Neuroscience
Volume21
Issue number2
DOIs
StatePublished - Feb 2014

Fingerprint

Intracranial Aneurysm
Aneurysm
Therapeutics
Rupture
Mortality
PubMed
France
Stents
Language
Arteries
Outcome Assessment (Health Care)
Equipment and Supplies

Keywords

  • Aneurysm occlusion
  • Endovascular treatment
  • Intracranial aneurysms
  • SILK flow diverter

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Physiology (medical)

Cite this

Murthy, S. B., Shah, S., Shastri, A., Venkatasubba Rao, C. P., Bershad, E. M., & Suarez, J. I. (2014). The SILK flow diverter in the treatment of intracranial aneurysms. Journal of Clinical Neuroscience, 21(2), 203-206. https://doi.org/10.1016/j.jocn.2013.07.006

The SILK flow diverter in the treatment of intracranial aneurysms. / Murthy, Santosh B.; Shah, Shreyansh; Shastri, Aditi; Venkatasubba Rao, Chethan P.; Bershad, Eric M.; Suarez, Jose I.

In: Journal of Clinical Neuroscience, Vol. 21, No. 2, 02.2014, p. 203-206.

Research output: Contribution to journalArticle

Murthy, SB, Shah, S, Shastri, A, Venkatasubba Rao, CP, Bershad, EM & Suarez, JI 2014, 'The SILK flow diverter in the treatment of intracranial aneurysms', Journal of Clinical Neuroscience, vol. 21, no. 2, pp. 203-206. https://doi.org/10.1016/j.jocn.2013.07.006
Murthy, Santosh B. ; Shah, Shreyansh ; Shastri, Aditi ; Venkatasubba Rao, Chethan P. ; Bershad, Eric M. ; Suarez, Jose I. / The SILK flow diverter in the treatment of intracranial aneurysms. In: Journal of Clinical Neuroscience. 2014 ; Vol. 21, No. 2. pp. 203-206.
@article{8f3947a0c77d4b13a16ac180f9611c04,
title = "The SILK flow diverter in the treatment of intracranial aneurysms",
abstract = "The SILK flow diverter (SFD; Balt Extrusion, Montmorency, France) is a flow diverting stent used in the endovascular treatment of intracranial aneurysms. It works on the principle of redirecting flow away from the aneurysm sac, leading to occlusion over time. We present a systematic review on the clinical outcomes and complications of the SFD. A literature search for English language articles were conducted on PubMed, Medline and EMBASE for articles on the treatment of intracranial aneurysms with the SILK flow diverter. The inclusion criteria were n > 10, use of SFD only, data on complications and aneurysm occlusion rate (AOR). Eight studies with 285 patients and 317 intracranial aneurysms were included. The mean age was 52.7 years and nearly 80{\%} were women. In terms of angiographic distribution, 86.8{\%} of aneurysms were located in the anterior circulation and 13.2{\%} in the posterior circulation. As for the aneurysm size, 37.9{\%} were classed as small, 44.4{\%} as large and 17.7{\%} as giant. Ischemic complications and parent artery occlusion each occurred in 10{\%} of patients. Aneurysm rupture rate was 3.5{\%}, while the cumulative mortality was 4.9{\%}. The main outcome measure, 12 month AOR, was 81.8{\%} with complete occlusion in 216 out of 264 aneurysms. Use of flow diverters for the treatment of intracranial aneurysm with complex morphologies has gained in popularity over the last few years. Our review suggests that SFD achieves comparable AOR to its contemporary, the Pipeline Embolization Device (ev3 Endovascular, Plymouth, MN, USA) but has a higher rate of higher rate of ischemic complications, aneurysm rupture and mortality.",
keywords = "Aneurysm occlusion, Endovascular treatment, Intracranial aneurysms, SILK flow diverter",
author = "Murthy, {Santosh B.} and Shreyansh Shah and Aditi Shastri and {Venkatasubba Rao}, {Chethan P.} and Bershad, {Eric M.} and Suarez, {Jose I.}",
year = "2014",
month = "2",
doi = "10.1016/j.jocn.2013.07.006",
language = "English (US)",
volume = "21",
pages = "203--206",
journal = "Journal of Clinical Neuroscience",
issn = "0967-5868",
publisher = "Churchill Livingstone",
number = "2",

}

TY - JOUR

T1 - The SILK flow diverter in the treatment of intracranial aneurysms

AU - Murthy, Santosh B.

AU - Shah, Shreyansh

AU - Shastri, Aditi

AU - Venkatasubba Rao, Chethan P.

AU - Bershad, Eric M.

AU - Suarez, Jose I.

PY - 2014/2

Y1 - 2014/2

N2 - The SILK flow diverter (SFD; Balt Extrusion, Montmorency, France) is a flow diverting stent used in the endovascular treatment of intracranial aneurysms. It works on the principle of redirecting flow away from the aneurysm sac, leading to occlusion over time. We present a systematic review on the clinical outcomes and complications of the SFD. A literature search for English language articles were conducted on PubMed, Medline and EMBASE for articles on the treatment of intracranial aneurysms with the SILK flow diverter. The inclusion criteria were n > 10, use of SFD only, data on complications and aneurysm occlusion rate (AOR). Eight studies with 285 patients and 317 intracranial aneurysms were included. The mean age was 52.7 years and nearly 80% were women. In terms of angiographic distribution, 86.8% of aneurysms were located in the anterior circulation and 13.2% in the posterior circulation. As for the aneurysm size, 37.9% were classed as small, 44.4% as large and 17.7% as giant. Ischemic complications and parent artery occlusion each occurred in 10% of patients. Aneurysm rupture rate was 3.5%, while the cumulative mortality was 4.9%. The main outcome measure, 12 month AOR, was 81.8% with complete occlusion in 216 out of 264 aneurysms. Use of flow diverters for the treatment of intracranial aneurysm with complex morphologies has gained in popularity over the last few years. Our review suggests that SFD achieves comparable AOR to its contemporary, the Pipeline Embolization Device (ev3 Endovascular, Plymouth, MN, USA) but has a higher rate of higher rate of ischemic complications, aneurysm rupture and mortality.

AB - The SILK flow diverter (SFD; Balt Extrusion, Montmorency, France) is a flow diverting stent used in the endovascular treatment of intracranial aneurysms. It works on the principle of redirecting flow away from the aneurysm sac, leading to occlusion over time. We present a systematic review on the clinical outcomes and complications of the SFD. A literature search for English language articles were conducted on PubMed, Medline and EMBASE for articles on the treatment of intracranial aneurysms with the SILK flow diverter. The inclusion criteria were n > 10, use of SFD only, data on complications and aneurysm occlusion rate (AOR). Eight studies with 285 patients and 317 intracranial aneurysms were included. The mean age was 52.7 years and nearly 80% were women. In terms of angiographic distribution, 86.8% of aneurysms were located in the anterior circulation and 13.2% in the posterior circulation. As for the aneurysm size, 37.9% were classed as small, 44.4% as large and 17.7% as giant. Ischemic complications and parent artery occlusion each occurred in 10% of patients. Aneurysm rupture rate was 3.5%, while the cumulative mortality was 4.9%. The main outcome measure, 12 month AOR, was 81.8% with complete occlusion in 216 out of 264 aneurysms. Use of flow diverters for the treatment of intracranial aneurysm with complex morphologies has gained in popularity over the last few years. Our review suggests that SFD achieves comparable AOR to its contemporary, the Pipeline Embolization Device (ev3 Endovascular, Plymouth, MN, USA) but has a higher rate of higher rate of ischemic complications, aneurysm rupture and mortality.

KW - Aneurysm occlusion

KW - Endovascular treatment

KW - Intracranial aneurysms

KW - SILK flow diverter

UR - http://www.scopus.com/inward/record.url?scp=84892574434&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84892574434&partnerID=8YFLogxK

U2 - 10.1016/j.jocn.2013.07.006

DO - 10.1016/j.jocn.2013.07.006

M3 - Article

C2 - 24128768

AN - SCOPUS:84892574434

VL - 21

SP - 203

EP - 206

JO - Journal of Clinical Neuroscience

JF - Journal of Clinical Neuroscience

SN - 0967-5868

IS - 2

ER -