The role of socioeconomic status, depression, quality of life, and glycemic control in type 1 diabetes mellitus

Krishnavathana Hassan, Robert Loar, Barbara J. Anderson, Rubina A. Heptulla

Research output: Contribution to journalArticle

164 Citations (Scopus)

Abstract

Objective: To test the hypothesis that poor glycemic control in type 1 diabetes mellitus (T1DM) is associated with depression and poor quality of life (QOL), with a higher prevalence in persons of lower socioeconomic status (SES). Study design: Subjects with T1DM age 8 to 17 years (n = 222) were evaluated using the Childrens Depression Inventory, the Hollingshead Four-Factor Index to determine SES, and PedsQL questionnaires to ascertain QOL. HbAlC > 8% was considered indicative of poor glycemic control. Results: A total of 110 well-controlled subjects and 112 poorly controlled subjects (HbA1C 7.1% ± 0.7% vs 9.9% ± 1.6%) were recruited. It was found that 9.5% of poorly controlled subjects were depressed, compared with 3% of well-controlled subjects. Logistic regression revealed a 27% increase in probability of depression per unit rise in HbA1C (P < .03). Higher SES was associated with better glycemic control (P < .0005) and QOL (P < .0005); longer duration of illness was not associated with poorer glycemic control. Diabetes QOL deteriorated with poorer glycemic control (P < .002). Conclusions: Poor glycemic control in peridatric T1DM is associated with lower SES and depression. The probability of depression increases as glycemic control worsens. Screening for depression should be routinely carried out in patients with T1DM, targeting patients with deteriorating glycemic control.

Original languageEnglish (US)
Pages (from-to)526-531
Number of pages6
JournalJournal of Pediatrics
Volume149
Issue number4
DOIs
StatePublished - Oct 2006
Externally publishedYes

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Type 1 Diabetes Mellitus
Social Class
Quality of Life
Logistic Models
Equipment and Supplies

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

The role of socioeconomic status, depression, quality of life, and glycemic control in type 1 diabetes mellitus. / Hassan, Krishnavathana; Loar, Robert; Anderson, Barbara J.; Heptulla, Rubina A.

In: Journal of Pediatrics, Vol. 149, No. 4, 10.2006, p. 526-531.

Research output: Contribution to journalArticle

Hassan, Krishnavathana ; Loar, Robert ; Anderson, Barbara J. ; Heptulla, Rubina A. / The role of socioeconomic status, depression, quality of life, and glycemic control in type 1 diabetes mellitus. In: Journal of Pediatrics. 2006 ; Vol. 149, No. 4. pp. 526-531.
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