Abstract
Breast cancer is the most frequently diagnosed malignancy among American women. It is the second most common cause of cancer death. Genetic analysis using comparative genetic hybridization (CGH) has shown evidence that the majority of breast cancers, approximately 85%, begin in the ductal epithelium with normal cells progressing to atypia and finally to carcinoma. Mammary ductoscopy, also referred to as the intraductal approach, is a new tool that allows direct visualization of the breast ductal system. It enables one to sample the ductal epithelium and may allow identification of early changes cytologically as well as potentially play an important role in aiding surgical excision. This may aid in detection of breast masses long before they are palpable or visible via mammography. Mammary ductoscopy may have a role in the evaluation of women with nipple discharge, high-risk women, or limiting the amount of tissue removed in breast conservation surgery for cancer.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3350-3360 |
| Number of pages | 11 |
| Journal | Annals of Surgical Oncology |
| Volume | 15 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1 2008 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Surgery
- Oncology
Cite this
The role of mammary ductoscopy in breast cancer : A review of the literature. / Kapenhas-Valdes, Edna; Feldman, Sheldon M.; Boolbol, Susan K.
In: Annals of Surgical Oncology, Vol. 15, No. 12, 01.12.2008, p. 3350-3360.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - The role of mammary ductoscopy in breast cancer
T2 - A review of the literature
AU - Kapenhas-Valdes, Edna
AU - Feldman, Sheldon M.
AU - Boolbol, Susan K.
PY - 2008/12/1
Y1 - 2008/12/1
N2 - Breast cancer is the most frequently diagnosed malignancy among American women. It is the second most common cause of cancer death. Genetic analysis using comparative genetic hybridization (CGH) has shown evidence that the majority of breast cancers, approximately 85%, begin in the ductal epithelium with normal cells progressing to atypia and finally to carcinoma. Mammary ductoscopy, also referred to as the intraductal approach, is a new tool that allows direct visualization of the breast ductal system. It enables one to sample the ductal epithelium and may allow identification of early changes cytologically as well as potentially play an important role in aiding surgical excision. This may aid in detection of breast masses long before they are palpable or visible via mammography. Mammary ductoscopy may have a role in the evaluation of women with nipple discharge, high-risk women, or limiting the amount of tissue removed in breast conservation surgery for cancer.
AB - Breast cancer is the most frequently diagnosed malignancy among American women. It is the second most common cause of cancer death. Genetic analysis using comparative genetic hybridization (CGH) has shown evidence that the majority of breast cancers, approximately 85%, begin in the ductal epithelium with normal cells progressing to atypia and finally to carcinoma. Mammary ductoscopy, also referred to as the intraductal approach, is a new tool that allows direct visualization of the breast ductal system. It enables one to sample the ductal epithelium and may allow identification of early changes cytologically as well as potentially play an important role in aiding surgical excision. This may aid in detection of breast masses long before they are palpable or visible via mammography. Mammary ductoscopy may have a role in the evaluation of women with nipple discharge, high-risk women, or limiting the amount of tissue removed in breast conservation surgery for cancer.
UR - http://www.scopus.com/inward/record.url?scp=58149296311&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=58149296311&partnerID=8YFLogxK
U2 - 10.1245/s10434-008-9911-4
DO - 10.1245/s10434-008-9911-4
M3 - Review article
C2 - 18841418
AN - SCOPUS:58149296311
VL - 15
SP - 3350
EP - 3360
JO - Annals of Surgical Oncology
JF - Annals of Surgical Oncology
SN - 1068-9265
IS - 12
ER -