The reparative function of cardiomyocytes in the infarcted myocardium

Research output: Contribution to journalShort surveypeer-review

7 Scopus citations

Abstract

Effective repair of the infarcted heart requires spatial containment of the inflammatory reaction within the infarcted area. A recently published study demonstrates that in the pro-inflammatory environment of the infarct border zone, surviving cardiomyocytes restrain inflammation by activating a Reg3β-dependent cascade that recruits reparative macrophages and promotes neutrophil clearance.

Original languageEnglish (US)
Pages (from-to)797-798
Number of pages2
JournalCell metabolism
Volume21
Issue number6
DOIs
StatePublished - Jun 2 2015

ASJC Scopus subject areas

  • Physiology
  • Molecular Biology
  • Cell Biology

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