TY - JOUR
T1 - The relationship between renal scarring and stone disease
AU - Newhouse, J. H.
AU - Amis, E. S.
PY - 1988
Y1 - 1988
N2 - The urographic findings of focal clubbing of the renal calices and associated parenchymcal scarring usually prompt a diagnosis of chronic pyelonephritis, which is frequently thought to be due to ongoing or previous vesicoureteral reflux. However, we noticed that upper tract stone disease appeared to be the condition that most often preceded or accompanied caliceal clubbing and parenchymal scarring in adults. To test the hypothesis that stones were the most common cause of this renal abnormality, we analyzed the IV urograms in 1500 consecutive patients for evidence of upper tract stone disease, vesicoureteral reflux, and caliceal clubbing and scarring. Of 39 patients with clubbing and scarring, 67% had stone disease, but only 8% had a history of reflux. Of 90 patients with stone disease, 29% had clubbing and scarring. We conclude that, in adults, upper tract stone disease may be the most important etiologic factor in the production of renal caliceal clubbing and scarring.
AB - The urographic findings of focal clubbing of the renal calices and associated parenchymcal scarring usually prompt a diagnosis of chronic pyelonephritis, which is frequently thought to be due to ongoing or previous vesicoureteral reflux. However, we noticed that upper tract stone disease appeared to be the condition that most often preceded or accompanied caliceal clubbing and parenchymal scarring in adults. To test the hypothesis that stones were the most common cause of this renal abnormality, we analyzed the IV urograms in 1500 consecutive patients for evidence of upper tract stone disease, vesicoureteral reflux, and caliceal clubbing and scarring. Of 39 patients with clubbing and scarring, 67% had stone disease, but only 8% had a history of reflux. Of 90 patients with stone disease, 29% had clubbing and scarring. We conclude that, in adults, upper tract stone disease may be the most important etiologic factor in the production of renal caliceal clubbing and scarring.
UR - http://www.scopus.com/inward/record.url?scp=0023744113&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0023744113&partnerID=8YFLogxK
U2 - 10.2214/ajr.151.6.1153
DO - 10.2214/ajr.151.6.1153
M3 - Article
C2 - 3263768
AN - SCOPUS:0023744113
VL - 151
SP - 1153
EP - 1156
JO - The American journal of roentgenology and radium therapy
JF - The American journal of roentgenology and radium therapy
SN - 0361-803X
IS - 6
ER -