The regulatory C-terminal domain of subunit ε of FoF1 ATP synthase is dispensable for growth and survival of Escherichia coli

Naohiro Taniguchi, Toshiharu Suzuki, Michael Berney, Masasuke Yoshida, Gregory M. Cook

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The C-terminal domain of subunit ε of the bacterial FoF1 ATP synthase is reported to be an intrinsic inhibitor of ATP synthesis/hydrolysis activity in vitro, preventing wasteful hydrolysis of ATP under low-energy conditions. Mutants defective in this regulatory domain exhibited no significant difference in growth rate, molar growth yield, membrane potential, or intracellular ATP concentration under a wide range of growth conditions and stressors compared to wild-type cells, suggesting this inhibitory domain is dispensable for growth and survival of Escherichia coli.

Original languageEnglish (US)
Pages (from-to)2046-2052
Number of pages7
JournalJournal of Bacteriology
Volume193
Issue number8
DOIs
StatePublished - Apr 2011
Externally publishedYes

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Adenosine Triphosphate
Escherichia coli
Growth
Hydrolysis
Membrane Potentials

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

Cite this

The regulatory C-terminal domain of subunit ε of FoF1 ATP synthase is dispensable for growth and survival of Escherichia coli. / Taniguchi, Naohiro; Suzuki, Toshiharu; Berney, Michael; Yoshida, Masasuke; Cook, Gregory M.

In: Journal of Bacteriology, Vol. 193, No. 8, 04.2011, p. 2046-2052.

Research output: Contribution to journalArticle

Taniguchi, Naohiro ; Suzuki, Toshiharu ; Berney, Michael ; Yoshida, Masasuke ; Cook, Gregory M. / The regulatory C-terminal domain of subunit ε of FoF1 ATP synthase is dispensable for growth and survival of Escherichia coli. In: Journal of Bacteriology. 2011 ; Vol. 193, No. 8. pp. 2046-2052.
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