The preventive treatment of migraine

Marcelo E. Bigal, Richard B. Lipton

Research output: Contribution to journalReview article

26 Scopus citations

Abstract

BACKGROUND: Migraine is a common, chronic, and disabling disorder. The treatment of migraine includes a combination of nonpharmacologic and pharmacologic techniques. Pharmacologic approaches are subdivided in preventive therapies and acute care. REVIEW SUMMARY: In this review article, we review the current approaches to the preventive treatment of migraine. Preventive treatment should be initiated in those with frequent or disabling headaches. The goals include (1) reducing attack frequency, intensity, and duration; (2) minimizing headache-related disability; (3) improving health-related quality of life; (4) avoiding headache escalation and medication misuse. In this article, we also discuss the principles of migraine prevention, as well as drugs available for this goal. We divide preventive medications on those of common use, nutraceutical compounds, and medications less frequently used. We close by briefly discussing some in-development potential preventive drugs. CONCLUSION: Preventive therapies are well suitable for migraineurs with attack-related disability despite appropriate acute care.

Original languageEnglish (US)
Pages (from-to)204-213
Number of pages10
JournalNeurologist
Volume12
Issue number4
DOIs
StatePublished - Jul 1 2006

Keywords

  • Migraine prevention
  • Preventive treatment

ASJC Scopus subject areas

  • Clinical Neurology

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