The prevalence of genuine empty follicle syndrome

Tolga B. Mesen, Bo Yu, Kevin S. Richter, Eric Widra, Alan H. DeCherney, James H. Segars

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Objective: To describe the prevalence of "genuine" empty follicle syndrome (EFS) and "false" EFS at assisted reproductive technology (ART). Design: Retrospective cohort. Setting: Large private fertility center. Patient(s): A total of 12,359 patients who underwent ART between 2004 and 2009. Intervention(s): None. Main Outcome Measure(s): The failure to recover an oocyte during oocyte retrieval at ART, with and without a detectable serum β-hCG on the day of retrieval. Result(s): Two cases of genuine EFS and nine cases of false EFS were identified in the cohort examined. The prevalence of genuine EFS was 0.016%, and the prevalence of false EFS was 0.072%. Only two out of 11 cases of EFS were considered genuine. Conclusion(s): Genuine EFS is a rare occurrence. Because this syndrome tends to recur with dismal pregnancy rates at ART, continued identification and further investigation of the syndrome are needed.

Original languageEnglish (US)
Pages (from-to)1375-1377
Number of pages3
JournalFertility and Sterility
Volume96
Issue number6
DOIs
StatePublished - Dec 2011
Externally publishedYes

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Assisted Reproductive Techniques
Oocyte Retrieval
Pregnancy Rate
Oocytes
Fertility
Outcome Assessment (Health Care)
Serum

Keywords

  • assisted reproduction
  • Empty follicle syndrome
  • follicle development
  • follicle maturation
  • hCG resistance
  • oocyte apoptosis
  • oocyte development
  • oocyte maturation failure

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Mesen, T. B., Yu, B., Richter, K. S., Widra, E., DeCherney, A. H., & Segars, J. H. (2011). The prevalence of genuine empty follicle syndrome. Fertility and Sterility, 96(6), 1375-1377. https://doi.org/10.1016/j.fertnstert.2011.09.047

The prevalence of genuine empty follicle syndrome. / Mesen, Tolga B.; Yu, Bo; Richter, Kevin S.; Widra, Eric; DeCherney, Alan H.; Segars, James H.

In: Fertility and Sterility, Vol. 96, No. 6, 12.2011, p. 1375-1377.

Research output: Contribution to journalArticle

Mesen, TB, Yu, B, Richter, KS, Widra, E, DeCherney, AH & Segars, JH 2011, 'The prevalence of genuine empty follicle syndrome', Fertility and Sterility, vol. 96, no. 6, pp. 1375-1377. https://doi.org/10.1016/j.fertnstert.2011.09.047
Mesen TB, Yu B, Richter KS, Widra E, DeCherney AH, Segars JH. The prevalence of genuine empty follicle syndrome. Fertility and Sterility. 2011 Dec;96(6):1375-1377. https://doi.org/10.1016/j.fertnstert.2011.09.047
Mesen, Tolga B. ; Yu, Bo ; Richter, Kevin S. ; Widra, Eric ; DeCherney, Alan H. ; Segars, James H. / The prevalence of genuine empty follicle syndrome. In: Fertility and Sterility. 2011 ; Vol. 96, No. 6. pp. 1375-1377.
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