The Prevalence and Pathobiology of Nonalcoholic Fatty Liver Disease in Patients of Different Races or Ethnicities

Harmit S. Kalia, Paul J. Gaglio

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Nonalcoholic fatty liver disease (NAFLD) is emerging as the most common cause of liver disease in the United States. The prevalence varies dramatically when comparing individuals of different races and ethnicities. Rates are highest in Hispanic patient populations compared with non-Hispanic whites and African Americans, despite similar rates of the metabolic syndrome and risk factors. This observation remains poorly characterized; variations in genes that effect lipid metabolism may play a role. This article describes the prevalence of NAFLD in patients of different races or ethnicities, and discusses pathophysiologic mechanisms that may explain why these differences exist.

Original languageEnglish (US)
JournalClinics in Liver Disease
DOIs
StateAccepted/In press - 2016

Fingerprint

Lipid Metabolism
Hispanic Americans
African Americans
Liver Diseases
Population
Genes
Non-alcoholic Fatty Liver Disease

Keywords

  • Ethnicity
  • NAFLD
  • PNPLA
  • Race

ASJC Scopus subject areas

  • Hepatology

Cite this

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