The oxidation-reduction potential of copper-bleomycin

Dean L. Melnyk, Susan Band Horwitz, Jack Peisach

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The oxidation-reduction potential of Cu(II)-bleomycin was measured at 25 °C, pH 7.0. With dithionite as reductant, the potential was -105 ± 9 mV with an n value near unity. With cysteine as reductant, the potential was -49 ± 10 mV, with an n value substantially greater than unity. The potentials are within a range that would allow the reduction of Cu(II)-bleomycin to take place in a cell.

Original languageEnglish (US)
Pages (from-to)75-78
Number of pages4
JournalInorganica Chimica Acta
Volume138
Issue number1
DOIs
StatePublished - 1987

Fingerprint

Reducing Agents
Bleomycin
Oxidation-Reduction
Dithionite
Copper
copper
oxidation
Cysteine
unity
cysteine
copper bleomycin
cells

ASJC Scopus subject areas

  • Biochemistry
  • Inorganic Chemistry
  • Physical and Theoretical Chemistry
  • Materials Chemistry

Cite this

The oxidation-reduction potential of copper-bleomycin. / Melnyk, Dean L.; Band Horwitz, Susan; Peisach, Jack.

In: Inorganica Chimica Acta, Vol. 138, No. 1, 1987, p. 75-78.

Research output: Contribution to journalArticle

Melnyk, Dean L. ; Band Horwitz, Susan ; Peisach, Jack. / The oxidation-reduction potential of copper-bleomycin. In: Inorganica Chimica Acta. 1987 ; Vol. 138, No. 1. pp. 75-78.
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