Abstract
Electrophysiological studies have revealed a pre-attentive change-detection system in the auditory modality. This system emits a signal termed the mismatch negativity (MMN) when any detectable change in a regular pattern of auditory stimulation occurs. The precise intracranial sources underlying MMN generation, and in particular whether these vary as a function of the acoustic feature that changes, is a matter of some debate. Using functional magnetic resonance imaging, we show that anatomically distinct networks of auditory cortices are activated as a function of the deviating acoustic feature - in this case, tone frequency and tone duration - strongly supporting the hypothesis that MMN generators in auditory cortex are feature dependent. We also detail regions of the frontal and parietal cortices activated by change-detection processes. These regions also show feature dependence and we hypothesize that they reflect recruitment of attention-switching mechanisms.
Original language | English (US) |
---|---|
Pages (from-to) | 545-551 |
Number of pages | 7 |
Journal | Cerebral Cortex |
Volume | 15 |
Issue number | 5 |
DOIs | |
State | Published - May 2005 |
Keywords
- Auditory
- Change-detection
- MMN
- Pre-attentive
- fMRI
ASJC Scopus subject areas
- Cognitive Neuroscience
- Cellular and Molecular Neuroscience