The need for liver biopsy in a patient with acute HCV infection

Wayne Tsuang, Ram Subramanian, Qiang Liu, John Hart, Smruti R. Mohanty

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: A 45-year-old white female was admitted to hospital with a 1-week history of right upper quadrant abdominal pain, progressive tiredness and jaundice. Physical examination confirmed jaundice and revealed mild epigastric tenderness. Laboratory test results revealed an extremely elevated alanine aminotransferase concentration, a high bilirubin concentration, the presence of HCV RNA, and a significantly elevated antinuclear antibody titer. Investigations: History and physical examination, laboratory investigations (including complete blood counts, liver function tests, electrolyte analysis, serological and genetic tests), Doppler ultrasound and CT scan of the abdomen, and liver biopsy. Diagnosis: Acute infection with HCV genotype 1a. Management: Supportive care, which included monitoring vital signs and laboratory test results, and management of acute symptoms.

Original languageEnglish (US)
Pages (from-to)54-57
Number of pages4
JournalNature Clinical Practice Gastroenterology and Hepatology
Volume5
Issue number1
DOIs
StatePublished - Jan 2008
Externally publishedYes

Fingerprint

Jaundice
Biopsy
Physical Examination
Liver
Infection
Doppler Ultrasonography
Blood Cell Count
Vital Signs
Liver Function Tests
Antinuclear Antibodies
Serologic Tests
Alanine Transaminase
Bilirubin
Abdomen
Abdominal Pain
Electrolytes
History
Genotype
RNA

ASJC Scopus subject areas

  • Gastroenterology
  • Hepatology

Cite this

The need for liver biopsy in a patient with acute HCV infection. / Tsuang, Wayne; Subramanian, Ram; Liu, Qiang; Hart, John; Mohanty, Smruti R.

In: Nature Clinical Practice Gastroenterology and Hepatology, Vol. 5, No. 1, 01.2008, p. 54-57.

Research output: Contribution to journalArticle

Tsuang, Wayne ; Subramanian, Ram ; Liu, Qiang ; Hart, John ; Mohanty, Smruti R. / The need for liver biopsy in a patient with acute HCV infection. In: Nature Clinical Practice Gastroenterology and Hepatology. 2008 ; Vol. 5, No. 1. pp. 54-57.
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