The Molecular Weight of Colony-Stimulating Factor (CSF)

E. R. Stanley, D. Metcalf

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

The apparent molecular weight of human urine CSF determined by gel filtration on Sephadex gels varied inversely with the purity of the preparation (190,000-60,000 mol wt). The apparent molecular weights calculated from zone sedimentation data on sucrose gradients and gradient polyacrylamide gel electrophoresis, as well as indirect evidence from polyacrylamide disc electrophoresis, were all consistent with an estimate of 45,000, irrespective of the purity of the preparations used.

Original languageEnglish (US)
Pages (from-to)1029-1031
Number of pages3
JournalProceedings of the Society for Experimental Biology and Medicine
Volume137
Issue number3
DOIs
StatePublished - Jul 1971

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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