The mineral disorders in pediatrics

Michael Linshaw, Michael Aigbe, Frederick J. Kaskel

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

There is increasing awareness of the role that metals/minerals play in health and disease. Minerals contribute in essential ways to the fundamental biochemical and physiological functions of cells. Deficit of an essential mineral leads to aberrations in cell function. Alternatively, minerals in excess have significant toxicity, and in an era of increasing threat to a safe environment, the potential for toxic tissue injury to contribute to progressive renal insufficiency and ultimately to unexplained renal failure remains a major concern. This review provides information on selected minerals that are attracting growing attention with respect to their influence on renal function in health and disease. Although all minerals have the potential to cause toxicity if consumed in sufficient quantity, most are essential nutrients whose deficiency is associated with significant health problems. Certain minerals, including aluminum, arsenic, cadmium, lead, and mercury are considered toxic. Their suggested positive effects on the health of animals has been recently summarized, but in humans they are not currently known to exert any clearly beneficial biological or biochemical effect.

Original languageEnglish (US)
Pages (from-to)280-294
Number of pages15
JournalSeminars in Nephrology
Volume18
Issue number3
StatePublished - 1998
Externally publishedYes

Fingerprint

Minerals
Pediatrics
Poisons
Health
Renal Insufficiency
Arsenic
Aluminum
Mercury
Cadmium
Metals
Kidney
Food
Wounds and Injuries

ASJC Scopus subject areas

  • Nephrology

Cite this

Linshaw, M., Aigbe, M., & Kaskel, F. J. (1998). The mineral disorders in pediatrics. Seminars in Nephrology, 18(3), 280-294.

The mineral disorders in pediatrics. / Linshaw, Michael; Aigbe, Michael; Kaskel, Frederick J.

In: Seminars in Nephrology, Vol. 18, No. 3, 1998, p. 280-294.

Research output: Contribution to journalArticle

Linshaw, M, Aigbe, M & Kaskel, FJ 1998, 'The mineral disorders in pediatrics', Seminars in Nephrology, vol. 18, no. 3, pp. 280-294.
Linshaw, Michael ; Aigbe, Michael ; Kaskel, Frederick J. / The mineral disorders in pediatrics. In: Seminars in Nephrology. 1998 ; Vol. 18, No. 3. pp. 280-294.
@article{57ac25a0dfd547da9b1705d623faf728,
title = "The mineral disorders in pediatrics",
abstract = "There is increasing awareness of the role that metals/minerals play in health and disease. Minerals contribute in essential ways to the fundamental biochemical and physiological functions of cells. Deficit of an essential mineral leads to aberrations in cell function. Alternatively, minerals in excess have significant toxicity, and in an era of increasing threat to a safe environment, the potential for toxic tissue injury to contribute to progressive renal insufficiency and ultimately to unexplained renal failure remains a major concern. This review provides information on selected minerals that are attracting growing attention with respect to their influence on renal function in health and disease. Although all minerals have the potential to cause toxicity if consumed in sufficient quantity, most are essential nutrients whose deficiency is associated with significant health problems. Certain minerals, including aluminum, arsenic, cadmium, lead, and mercury are considered toxic. Their suggested positive effects on the health of animals has been recently summarized, but in humans they are not currently known to exert any clearly beneficial biological or biochemical effect.",
author = "Michael Linshaw and Michael Aigbe and Kaskel, {Frederick J.}",
year = "1998",
language = "English (US)",
volume = "18",
pages = "280--294",
journal = "Seminars in Nephrology",
issn = "0270-9295",
publisher = "W.B. Saunders Ltd",
number = "3",

}

TY - JOUR

T1 - The mineral disorders in pediatrics

AU - Linshaw, Michael

AU - Aigbe, Michael

AU - Kaskel, Frederick J.

PY - 1998

Y1 - 1998

N2 - There is increasing awareness of the role that metals/minerals play in health and disease. Minerals contribute in essential ways to the fundamental biochemical and physiological functions of cells. Deficit of an essential mineral leads to aberrations in cell function. Alternatively, minerals in excess have significant toxicity, and in an era of increasing threat to a safe environment, the potential for toxic tissue injury to contribute to progressive renal insufficiency and ultimately to unexplained renal failure remains a major concern. This review provides information on selected minerals that are attracting growing attention with respect to their influence on renal function in health and disease. Although all minerals have the potential to cause toxicity if consumed in sufficient quantity, most are essential nutrients whose deficiency is associated with significant health problems. Certain minerals, including aluminum, arsenic, cadmium, lead, and mercury are considered toxic. Their suggested positive effects on the health of animals has been recently summarized, but in humans they are not currently known to exert any clearly beneficial biological or biochemical effect.

AB - There is increasing awareness of the role that metals/minerals play in health and disease. Minerals contribute in essential ways to the fundamental biochemical and physiological functions of cells. Deficit of an essential mineral leads to aberrations in cell function. Alternatively, minerals in excess have significant toxicity, and in an era of increasing threat to a safe environment, the potential for toxic tissue injury to contribute to progressive renal insufficiency and ultimately to unexplained renal failure remains a major concern. This review provides information on selected minerals that are attracting growing attention with respect to their influence on renal function in health and disease. Although all minerals have the potential to cause toxicity if consumed in sufficient quantity, most are essential nutrients whose deficiency is associated with significant health problems. Certain minerals, including aluminum, arsenic, cadmium, lead, and mercury are considered toxic. Their suggested positive effects on the health of animals has been recently summarized, but in humans they are not currently known to exert any clearly beneficial biological or biochemical effect.

UR - http://www.scopus.com/inward/record.url?scp=0031955697&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031955697&partnerID=8YFLogxK

M3 - Article

VL - 18

SP - 280

EP - 294

JO - Seminars in Nephrology

JF - Seminars in Nephrology

SN - 0270-9295

IS - 3

ER -