The Liver: Biology and Pathobiology: Fifth Edition

Irwin M. Arias, Harvey J. Alter, James L. Boyer, David E. Cohen, Nelson Fausto, David A. Shafritz, Allan W. Wolkoff

Research output: Book/ReportBook

17 Scopus citations


In its Fifth Edition, this classic book retains its traditional strength of relating molecular physiology to understanding disease pathology and treatment as it explores the current state and future direction of hepatology. Painstakingly revised, this edition includes 60 new chapters. As in previous editions, a section called Horizons summarizes advances of extraordinary nature in areas expected to have a substantial impact on hepatology. The Fifth Edition's Horizons section includes emerging topics such as tissue engineering of the liver, liver-directed gene therapy, decoding the liver cancer genome, and imaging cellular proteins and structure. To preserve essential background information which has not changed while making room for the panoply of major new contributions to understanding of liver disease, 14 chapters from the previous edition are freely available online at To view these chapters visit -

Original languageEnglish (US)
PublisherJohn Wiley and Sons
Number of pages1191
ISBN (Print)9780470723135
Publication statusPublished - Oct 6 2009


ASJC Scopus subject areas

  • Medicine(all)

Cite this

Arias, I. M., Alter, H. J., Boyer, J. L., Cohen, D. E., Fausto, N., Shafritz, D. A., & Wolkoff, A. W. (2009). The Liver: Biology and Pathobiology: Fifth Edition. John Wiley and Sons.