The Ins and Outs of MHC Class II Proteins in Dendritic Cells

Laura Santambrogio, Jack L. Strominger

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

One more mechanism for regulating surface expression of MHC class II proteins in dendritic cells (an important process that regulates both tolerance and immunity) has been uncovered, polyubiquitination of Lys225 in the intracytoplasmic region and subsequent endocytosis and proteolysis (Omura-Hoshino et al., 2006; van Neil et al., 2006; Shin et al., 2006).

Original languageEnglish (US)
Pages (from-to)857-859
Number of pages3
JournalImmunity
Volume25
Issue number6
DOIs
StatePublished - Dec 2006

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Endocytosis
Dendritic Cells
Proteolysis
Immunity
Proteins

ASJC Scopus subject areas

  • Immunology and Allergy
  • Infectious Diseases
  • Immunology

Cite this

The Ins and Outs of MHC Class II Proteins in Dendritic Cells. / Santambrogio, Laura; Strominger, Jack L.

In: Immunity, Vol. 25, No. 6, 12.2006, p. 857-859.

Research output: Contribution to journalArticle

Santambrogio, Laura ; Strominger, Jack L. / The Ins and Outs of MHC Class II Proteins in Dendritic Cells. In: Immunity. 2006 ; Vol. 25, No. 6. pp. 857-859.
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