The inhibition of vitamin K3 on rabbit fibroblast proliferation in vitro

Xin Hua Liu; Xiu Wen Song; Yan Xu; Cheng Zhang

doi:10.1159/000310703

The inhibition of vitamin K₃ on rabbit fibroblast proliferation in vitro

Xin Hua Liu, Xiu Wen Song, Yan Xu, Cheng Zhang

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Vitamin K₃ that is commonly used to treat hemorrhagic diseases can inhibit human lymphatic neoplasms in vitro. This study was undertaken to investigate the effects of vitamin K₃ on rabbit conjunctival fibroblast proliferation in cell culture. Vitamin K3 was added to cultured rabbit conjunctival fibroblasts. Remarkable inhibition was observed at a concentration of 4 mg/l. Because of its lower toxicity, vitamin K₃ may prove to be of significant value in the treatment of intraocular proliferative disorders.

Original language	English (US)
Pages (from-to)	180-182
Number of pages	3
Journal	Ophthalmologica
Volume	210
Issue number	3
DOIs	https://doi.org/10.1159/000310703
State	Published - Jan 1 1996
Externally published	Yes

Keywords

Cell culture
Fibroblast inhibition
Vitamin K

ASJC Scopus subject areas

Ophthalmology
Sensory Systems

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1159/000310703

Cite this

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abstract = "Vitamin K3 that is commonly used to treat hemorrhagic diseases can inhibit human lymphatic neoplasms in vitro. This study was undertaken to investigate the effects of vitamin K3 on rabbit conjunctival fibroblast proliferation in cell culture. Vitamin K3 was added to cultured rabbit conjunctival fibroblasts. Remarkable inhibition was observed at a concentration of 4 mg/l. Because of its lower toxicity, vitamin K3 may prove to be of significant value in the treatment of intraocular proliferative disorders.",

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AB - Vitamin K3 that is commonly used to treat hemorrhagic diseases can inhibit human lymphatic neoplasms in vitro. This study was undertaken to investigate the effects of vitamin K3 on rabbit conjunctival fibroblast proliferation in cell culture. Vitamin K3 was added to cultured rabbit conjunctival fibroblasts. Remarkable inhibition was observed at a concentration of 4 mg/l. Because of its lower toxicity, vitamin K3 may prove to be of significant value in the treatment of intraocular proliferative disorders.

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