The inhibition of vitamin K3 on rabbit fibroblast proliferation in vitro

Xin Hua Liu, Xiu Wen Song, Yan Xu, Cheng Zhang

Research output: Contribution to journalArticle

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Abstract

Vitamin K3 that is commonly used to treat hemorrhagic diseases can inhibit human lymphatic neoplasms in vitro. This study was undertaken to investigate the effects of vitamin K3 on rabbit conjunctival fibroblast proliferation in cell culture. Vitamin K3 was added to cultured rabbit conjunctival fibroblasts. Remarkable inhibition was observed at a concentration of 4 mg/l. Because of its lower toxicity, vitamin K3 may prove to be of significant value in the treatment of intraocular proliferative disorders.

Original languageEnglish (US)
Pages (from-to)180-182
Number of pages3
JournalOphthalmologica
Volume210
Issue number3
DOIs
Publication statusPublished - Jan 1 1996
Externally publishedYes

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Keywords

  • Cell culture
  • Fibroblast inhibition
  • Vitamin K

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

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