The Impact of Obesity on the Cardiovascular System

Imre Csige, Dóra Ujvárosy, Zoltán Szabó, István Lorincz, György Paragh, Mariann Harangi, Sándor Somodi, Gaetano Santulli

Research output: Contribution to journalReview article

30 Scopus citations

Abstract

Obesity is a growing health problem worldwide. It is associated with an increased cardiovascular risk on the one hand of obesity itself and on the other hand of associated medical conditions (hypertension, diabetes, insulin resistance, and sleep apnoea syndrome). Obesity has an important role in atherosclerosis and coronary artery disease. Obesity leads to structural and functional changes of the heart, which causes heart failure. The altered myocardial structure increases the risk of atrial fibrillation and sudden cardiac death. However, obesity also has a protective effect on the clinical outcome of underlying cardiovascular disease, the phenomenon called obesity paradox. The improved cardiac imaging techniques allow the early detection of altered structure and function of the heart in obese patients. In this review, we attempt to summarize the relationship between obesity and cardiovascular diseases and outline the underlying mechanisms. The demonstrated new techniques of cardiac diagnostic procedures allow for the early detection and treatment of subclinical medical conditions and, therefore, the prevention of cardiovascular events.

Original languageEnglish (US)
Article number3407306
JournalJournal of diabetes research
Volume2018
DOIs
StatePublished - Jan 1 2018
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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    Csige, I., Ujvárosy, D., Szabó, Z., Lorincz, I., Paragh, G., Harangi, M., Somodi, S., & Santulli, G. (2018). The Impact of Obesity on the Cardiovascular System. Journal of diabetes research, 2018, [3407306]. https://doi.org/10.1155/2018/3407306