The impact of metal artifacts on IMRT dose distributions in TCP and NTCP

Yusung Kim; Wolfgang A. Tomé

doi:10.1007/978-3-540-36841-0_433

The impact of metal artifacts on IMRT dose distributions in TCP and NTCP

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Purpose: To investigate the effects of distorted head-and-neck (H&N) IMRT dose distributions (hot and cold spots) on normal tissue complication probability (NTCP) and tumor control probability (TCP) due to dental-metal artifacts. Methods: Five patients’ IMRT treatment plans have been analyzed, employing five different planning image data-sets: (a) uncorrected (UC); (b) homogeneous uncorrected (HUC); (c) sinogram completion corrected (SCC); (d) minimum-valuecorrected (MVC); and (e) streak-artifact-reduction including minimum-value-correction (SAR-MVC), that has been taken as the reference data set. The effects on NTCP and TCP were evaluated using the Lyman-NTCP model and the Logistic TCP model, respectively. Results: When compared to the predicted NTCP using the reference data set, the treatment plan based on the original CT data-set (UC) yielded an increase of 3.2% and 2.0% in NTCP for the spared parotid gland and the spinal cord. While the treatment plans based on the MVC CT data set NTCP increased by 1.1% and 0.1% for the spared parotid and the spinal cord. In addition, the MVC correction method showed reduced ΔTCP (MVC: 0.6% vs. UC: 1.3%) with respect to that of the reference CT data set. Conclusion: Our results indicate that the presence of dental- metal-artifacts in H&N planning CT data sets has an impact on the estimates of TCP and NTCP. In particular dentalmetal- artifacts lead to an increase in NTCP for the spared parotid and a slight decrease in TCP for TV.

Original language	English (US)
Title of host publication	IFMBE Proceedings
Editors	Sun I. Kim, Tae Suk Suh
Publisher	Springer Verlag
Pages	1750-1753
Number of pages	4
Edition	1
ISBN (Print)	9783540368397
DOIs	https://doi.org/10.1007/978-3-540-36841-0_433
State	Published - 2007
Externally published	Yes
Event	10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of Duration: Aug 27 2006 → Sep 1 2006

Publication series

Name	IFMBE Proceedings
Number	1
Volume	14
ISSN (Print)	1680-0737
ISSN (Electronic)	1433-9277

Other

Other	10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
Country/Territory	Korea, Republic of
City	Seoul
Period	8/27/06 → 9/1/06

Keywords

Head and neck
Metal artifacts
NTCP
TCP
Treatment planning

ASJC Scopus subject areas

Bioengineering
Biomedical Engineering

Access to Document

10.1007/978-3-540-36841-0_433

Cite this

Kim, Y & Tomé, WA 2007, The impact of metal artifacts on IMRT dose distributions in TCP and NTCP. in SI Kim & TS Suh (eds), IFMBE Proceedings. 1 edn, IFMBE Proceedings, no. 1, vol. 14, Springer Verlag, pp. 1750-1753, 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006, Seoul, Korea, Republic of, 8/27/06. https://doi.org/10.1007/978-3-540-36841-0_433

@inproceedings{cdb3bd47a8364904b180a777161dfeb4,

title = "The impact of metal artifacts on IMRT dose distributions in TCP and NTCP",

abstract = "Purpose: To investigate the effects of distorted head-and-neck (H&N) IMRT dose distributions (hot and cold spots) on normal tissue complication probability (NTCP) and tumor control probability (TCP) due to dental-metal artifacts. Methods: Five patients{\textquoteright} IMRT treatment plans have been analyzed, employing five different planning image data-sets: (a) uncorrected (UC); (b) homogeneous uncorrected (HUC); (c) sinogram completion corrected (SCC); (d) minimum-valuecorrected (MVC); and (e) streak-artifact-reduction including minimum-value-correction (SAR-MVC), that has been taken as the reference data set. The effects on NTCP and TCP were evaluated using the Lyman-NTCP model and the Logistic TCP model, respectively. Results: When compared to the predicted NTCP using the reference data set, the treatment plan based on the original CT data-set (UC) yielded an increase of 3.2% and 2.0% in NTCP for the spared parotid gland and the spinal cord. While the treatment plans based on the MVC CT data set NTCP increased by 1.1% and 0.1% for the spared parotid and the spinal cord. In addition, the MVC correction method showed reduced ΔTCP (MVC: 0.6% vs. UC: 1.3%) with respect to that of the reference CT data set. Conclusion: Our results indicate that the presence of dental- metal-artifacts in H&N planning CT data sets has an impact on the estimates of TCP and NTCP. In particular dentalmetal- artifacts lead to an increase in NTCP for the spared parotid and a slight decrease in TCP for TV.",

keywords = "Head and neck, Metal artifacts, NTCP, TCP, Treatment planning",

author = "Yusung Kim and Tom{\'e}, {Wolfgang A.}",

note = "Publisher Copyright: {\textcopyright} International Federation for Medical and Biological Engineering 2007.; 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 ; Conference date: 27-08-2006 Through 01-09-2006",

year = "2007",

doi = "10.1007/978-3-540-36841-0_433",

language = "English (US)",

isbn = "9783540368397",

series = "IFMBE Proceedings",

publisher = "Springer Verlag",

number = "1",

pages = "1750--1753",

editor = "Kim, {Sun I.} and Suh, {Tae Suk}",

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edition = "1",

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TY - GEN

T1 - The impact of metal artifacts on IMRT dose distributions in TCP and NTCP

AU - Kim, Yusung

AU - Tomé, Wolfgang A.

N1 - Publisher Copyright: © International Federation for Medical and Biological Engineering 2007.

PY - 2007

Y1 - 2007

N2 - Purpose: To investigate the effects of distorted head-and-neck (H&N) IMRT dose distributions (hot and cold spots) on normal tissue complication probability (NTCP) and tumor control probability (TCP) due to dental-metal artifacts. Methods: Five patients’ IMRT treatment plans have been analyzed, employing five different planning image data-sets: (a) uncorrected (UC); (b) homogeneous uncorrected (HUC); (c) sinogram completion corrected (SCC); (d) minimum-valuecorrected (MVC); and (e) streak-artifact-reduction including minimum-value-correction (SAR-MVC), that has been taken as the reference data set. The effects on NTCP and TCP were evaluated using the Lyman-NTCP model and the Logistic TCP model, respectively. Results: When compared to the predicted NTCP using the reference data set, the treatment plan based on the original CT data-set (UC) yielded an increase of 3.2% and 2.0% in NTCP for the spared parotid gland and the spinal cord. While the treatment plans based on the MVC CT data set NTCP increased by 1.1% and 0.1% for the spared parotid and the spinal cord. In addition, the MVC correction method showed reduced ΔTCP (MVC: 0.6% vs. UC: 1.3%) with respect to that of the reference CT data set. Conclusion: Our results indicate that the presence of dental- metal-artifacts in H&N planning CT data sets has an impact on the estimates of TCP and NTCP. In particular dentalmetal- artifacts lead to an increase in NTCP for the spared parotid and a slight decrease in TCP for TV.

AB - Purpose: To investigate the effects of distorted head-and-neck (H&N) IMRT dose distributions (hot and cold spots) on normal tissue complication probability (NTCP) and tumor control probability (TCP) due to dental-metal artifacts. Methods: Five patients’ IMRT treatment plans have been analyzed, employing five different planning image data-sets: (a) uncorrected (UC); (b) homogeneous uncorrected (HUC); (c) sinogram completion corrected (SCC); (d) minimum-valuecorrected (MVC); and (e) streak-artifact-reduction including minimum-value-correction (SAR-MVC), that has been taken as the reference data set. The effects on NTCP and TCP were evaluated using the Lyman-NTCP model and the Logistic TCP model, respectively. Results: When compared to the predicted NTCP using the reference data set, the treatment plan based on the original CT data-set (UC) yielded an increase of 3.2% and 2.0% in NTCP for the spared parotid gland and the spinal cord. While the treatment plans based on the MVC CT data set NTCP increased by 1.1% and 0.1% for the spared parotid and the spinal cord. In addition, the MVC correction method showed reduced ΔTCP (MVC: 0.6% vs. UC: 1.3%) with respect to that of the reference CT data set. Conclusion: Our results indicate that the presence of dental- metal-artifacts in H&N planning CT data sets has an impact on the estimates of TCP and NTCP. In particular dentalmetal- artifacts lead to an increase in NTCP for the spared parotid and a slight decrease in TCP for TV.

KW - Head and neck

KW - Metal artifacts

KW - NTCP

KW - TCP

KW - Treatment planning

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U2 - 10.1007/978-3-540-36841-0_433

DO - 10.1007/978-3-540-36841-0_433

M3 - Conference contribution

AN - SCOPUS:84958240535

SN - 9783540368397

T3 - IFMBE Proceedings

SP - 1750

EP - 1753

BT - IFMBE Proceedings

A2 - Kim, Sun I.

A2 - Suh, Tae Suk

PB - Springer Verlag

T2 - 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006

Y2 - 27 August 2006 through 1 September 2006

ER -

The impact of metal artifacts on IMRT dose distributions in TCP and NTCP

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