The impact of metal artifacts on IMRT dose distributions in TCP and NTCP

Yusung Kim, Wolfgang A. Tome

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Purpose: To investigate the effects of distorted head-and-neck (H&N) IMRT dose distributions (hot and cold spots) on normal tissue complication probability (NTCP) and tumor control probability (TCP) due to dental-metal artifacts. Methods: Five patients’ IMRT treatment plans have been analyzed, employing five different planning image data-sets: (a) uncorrected (UC); (b) homogeneous uncorrected (HUC); (c) sinogram completion corrected (SCC); (d) minimum-valuecorrected (MVC); and (e) streak-artifact-reduction including minimum-value-correction (SAR-MVC), that has been taken as the reference data set. The effects on NTCP and TCP were evaluated using the Lyman-NTCP model and the Logistic TCP model, respectively. Results: When compared to the predicted NTCP using the reference data set, the treatment plan based on the original CT data-set (UC) yielded an increase of 3.2% and 2.0% in NTCP for the spared parotid gland and the spinal cord. While the treatment plans based on the MVC CT data set NTCP increased by 1.1% and 0.1% for the spared parotid and the spinal cord. In addition, the MVC correction method showed reduced ΔTCP (MVC: 0.6% vs. UC: 1.3%) with respect to that of the reference CT data set. Conclusion: Our results indicate that the presence of dental- metal-artifacts in H&N planning CT data sets has an impact on the estimates of TCP and NTCP. In particular dentalmetal- artifacts lead to an increase in NTCP for the spared parotid and a slight decrease in TCP for TV.

Original languageEnglish (US)
Title of host publicationIFMBE Proceedings
PublisherSpringer Verlag
Pages1750-1753
Number of pages4
Volume14
Edition1
StatePublished - 2007
Externally publishedYes
Event10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of
Duration: Aug 27 2006Sep 1 2006

Other

Other10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
CountryKorea, Republic of
CitySeoul
Period8/27/069/1/06

Fingerprint

Tumors
Metals
Tissue
Patient treatment
Planning
Logistics

Keywords

  • Head and neck
  • Metal artifacts
  • NTCP
  • TCP
  • Treatment planning

ASJC Scopus subject areas

  • Biomedical Engineering
  • Bioengineering

Cite this

Kim, Y., & Tome, W. A. (2007). The impact of metal artifacts on IMRT dose distributions in TCP and NTCP. In IFMBE Proceedings (1 ed., Vol. 14, pp. 1750-1753). Springer Verlag.

The impact of metal artifacts on IMRT dose distributions in TCP and NTCP. / Kim, Yusung; Tome, Wolfgang A.

IFMBE Proceedings. Vol. 14 1. ed. Springer Verlag, 2007. p. 1750-1753.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Kim, Y & Tome, WA 2007, The impact of metal artifacts on IMRT dose distributions in TCP and NTCP. in IFMBE Proceedings. 1 edn, vol. 14, Springer Verlag, pp. 1750-1753, 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006, Seoul, Korea, Republic of, 8/27/06.
Kim Y, Tome WA. The impact of metal artifacts on IMRT dose distributions in TCP and NTCP. In IFMBE Proceedings. 1 ed. Vol. 14. Springer Verlag. 2007. p. 1750-1753
Kim, Yusung ; Tome, Wolfgang A. / The impact of metal artifacts on IMRT dose distributions in TCP and NTCP. IFMBE Proceedings. Vol. 14 1. ed. Springer Verlag, 2007. pp. 1750-1753
@inproceedings{cdb3bd47a8364904b180a777161dfeb4,
title = "The impact of metal artifacts on IMRT dose distributions in TCP and NTCP",
abstract = "Purpose: To investigate the effects of distorted head-and-neck (H&N) IMRT dose distributions (hot and cold spots) on normal tissue complication probability (NTCP) and tumor control probability (TCP) due to dental-metal artifacts. Methods: Five patients’ IMRT treatment plans have been analyzed, employing five different planning image data-sets: (a) uncorrected (UC); (b) homogeneous uncorrected (HUC); (c) sinogram completion corrected (SCC); (d) minimum-valuecorrected (MVC); and (e) streak-artifact-reduction including minimum-value-correction (SAR-MVC), that has been taken as the reference data set. The effects on NTCP and TCP were evaluated using the Lyman-NTCP model and the Logistic TCP model, respectively. Results: When compared to the predicted NTCP using the reference data set, the treatment plan based on the original CT data-set (UC) yielded an increase of 3.2{\%} and 2.0{\%} in NTCP for the spared parotid gland and the spinal cord. While the treatment plans based on the MVC CT data set NTCP increased by 1.1{\%} and 0.1{\%} for the spared parotid and the spinal cord. In addition, the MVC correction method showed reduced ΔTCP (MVC: 0.6{\%} vs. UC: 1.3{\%}) with respect to that of the reference CT data set. Conclusion: Our results indicate that the presence of dental- metal-artifacts in H&N planning CT data sets has an impact on the estimates of TCP and NTCP. In particular dentalmetal- artifacts lead to an increase in NTCP for the spared parotid and a slight decrease in TCP for TV.",
keywords = "Head and neck, Metal artifacts, NTCP, TCP, Treatment planning",
author = "Yusung Kim and Tome, {Wolfgang A.}",
year = "2007",
language = "English (US)",
volume = "14",
pages = "1750--1753",
booktitle = "IFMBE Proceedings",
publisher = "Springer Verlag",
edition = "1",

}

TY - GEN

T1 - The impact of metal artifacts on IMRT dose distributions in TCP and NTCP

AU - Kim, Yusung

AU - Tome, Wolfgang A.

PY - 2007

Y1 - 2007

N2 - Purpose: To investigate the effects of distorted head-and-neck (H&N) IMRT dose distributions (hot and cold spots) on normal tissue complication probability (NTCP) and tumor control probability (TCP) due to dental-metal artifacts. Methods: Five patients’ IMRT treatment plans have been analyzed, employing five different planning image data-sets: (a) uncorrected (UC); (b) homogeneous uncorrected (HUC); (c) sinogram completion corrected (SCC); (d) minimum-valuecorrected (MVC); and (e) streak-artifact-reduction including minimum-value-correction (SAR-MVC), that has been taken as the reference data set. The effects on NTCP and TCP were evaluated using the Lyman-NTCP model and the Logistic TCP model, respectively. Results: When compared to the predicted NTCP using the reference data set, the treatment plan based on the original CT data-set (UC) yielded an increase of 3.2% and 2.0% in NTCP for the spared parotid gland and the spinal cord. While the treatment plans based on the MVC CT data set NTCP increased by 1.1% and 0.1% for the spared parotid and the spinal cord. In addition, the MVC correction method showed reduced ΔTCP (MVC: 0.6% vs. UC: 1.3%) with respect to that of the reference CT data set. Conclusion: Our results indicate that the presence of dental- metal-artifacts in H&N planning CT data sets has an impact on the estimates of TCP and NTCP. In particular dentalmetal- artifacts lead to an increase in NTCP for the spared parotid and a slight decrease in TCP for TV.

AB - Purpose: To investigate the effects of distorted head-and-neck (H&N) IMRT dose distributions (hot and cold spots) on normal tissue complication probability (NTCP) and tumor control probability (TCP) due to dental-metal artifacts. Methods: Five patients’ IMRT treatment plans have been analyzed, employing five different planning image data-sets: (a) uncorrected (UC); (b) homogeneous uncorrected (HUC); (c) sinogram completion corrected (SCC); (d) minimum-valuecorrected (MVC); and (e) streak-artifact-reduction including minimum-value-correction (SAR-MVC), that has been taken as the reference data set. The effects on NTCP and TCP were evaluated using the Lyman-NTCP model and the Logistic TCP model, respectively. Results: When compared to the predicted NTCP using the reference data set, the treatment plan based on the original CT data-set (UC) yielded an increase of 3.2% and 2.0% in NTCP for the spared parotid gland and the spinal cord. While the treatment plans based on the MVC CT data set NTCP increased by 1.1% and 0.1% for the spared parotid and the spinal cord. In addition, the MVC correction method showed reduced ΔTCP (MVC: 0.6% vs. UC: 1.3%) with respect to that of the reference CT data set. Conclusion: Our results indicate that the presence of dental- metal-artifacts in H&N planning CT data sets has an impact on the estimates of TCP and NTCP. In particular dentalmetal- artifacts lead to an increase in NTCP for the spared parotid and a slight decrease in TCP for TV.

KW - Head and neck

KW - Metal artifacts

KW - NTCP

KW - TCP

KW - Treatment planning

UR - http://www.scopus.com/inward/record.url?scp=84958240535&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84958240535&partnerID=8YFLogxK

M3 - Conference contribution

VL - 14

SP - 1750

EP - 1753

BT - IFMBE Proceedings

PB - Springer Verlag

ER -