The impact of metal artifacts on IMRT dose distributions in TCP and NTCP

Yusung Kim; Wolfgang A. Tomé

doi:10.1007/978-3-540-36841-0_433

The impact of metal artifacts on IMRT dose distributions in TCP and NTCP

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Purpose: To investigate the effects of distorted head-and-neck (H&N) IMRT dose distributions (hot and cold spots) on normal tissue complication probability (NTCP) and tumor control probability (TCP) due to dental-metal artifacts. Methods: Five patients’ IMRT treatment plans have been analyzed, employing five different planning image data-sets: (a) uncorrected (UC); (b) homogeneous uncorrected (HUC); (c) sinogram completion corrected (SCC); (d) minimum-valuecorrected (MVC); and (e) streak-artifact-reduction including minimum-value-correction (SAR-MVC), that has been taken as the reference data set. The effects on NTCP and TCP were evaluated using the Lyman-NTCP model and the Logistic TCP model, respectively. Results: When compared to the predicted NTCP using the reference data set, the treatment plan based on the original CT data-set (UC) yielded an increase of 3.2% and 2.0% in NTCP for the spared parotid gland and the spinal cord. While the treatment plans based on the MVC CT data set NTCP increased by 1.1% and 0.1% for the spared parotid and the spinal cord. In addition, the MVC correction method showed reduced ΔTCP (MVC: 0.6% vs. UC: 1.3%) with respect to that of the reference CT data set. Conclusion: Our results indicate that the presence of dental- metal-artifacts in H&N planning CT data sets has an impact on the estimates of TCP and NTCP. In particular dentalmetal- artifacts lead to an increase in NTCP for the spared parotid and a slight decrease in TCP for TV.

Original language	English (US)
Title of host publication	IFMBE Proceedings
Editors	Sun I. Kim, Tae Suk Suh
Publisher	Springer Verlag
Pages	1750-1753
Number of pages	4
Edition	1
ISBN (Print)	9783540368397
DOIs	https://doi.org/10.1007/978-3-540-36841-0_433
State	Published - Jan 1 2007
Externally published	Yes
Event	10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of Duration: Aug 27 2006 → Sep 1 2006

Publication series

Name	IFMBE Proceedings
Number	1
Volume	14
ISSN (Print)	1680-0737
ISSN (Electronic)	1433-9277

Other

Other	10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
Country/Territory	Korea, Republic of
City	Seoul
Period	8/27/06 → 9/1/06

Keywords

Head and neck
Metal artifacts
NTCP
TCP
Treatment planning

ASJC Scopus subject areas

Bioengineering
Biomedical Engineering

Access to Document

10.1007/978-3-540-36841-0_433

Cite this

Kim, Y & Tomé, WA 2007, The impact of metal artifacts on IMRT dose distributions in TCP and NTCP. in SI Kim & TS Suh (eds), IFMBE Proceedings. 1 edn, IFMBE Proceedings, no. 1, vol. 14, Springer Verlag, pp. 1750-1753, 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006, Seoul, Korea, Republic of, 8/27/06. https://doi.org/10.1007/978-3-540-36841-0_433

@inproceedings{cdb3bd47a8364904b180a777161dfeb4,

title = "The impact of metal artifacts on IMRT dose distributions in TCP and NTCP",

abstract = "Purpose: To investigate the effects of distorted head-and-neck (H&N) IMRT dose distributions (hot and cold spots) on normal tissue complication probability (NTCP) and tumor control probability (TCP) due to dental-metal artifacts. Methods: Five patients{\textquoteright} IMRT treatment plans have been analyzed, employing five different planning image data-sets: (a) uncorrected (UC); (b) homogeneous uncorrected (HUC); (c) sinogram completion corrected (SCC); (d) minimum-valuecorrected (MVC); and (e) streak-artifact-reduction including minimum-value-correction (SAR-MVC), that has been taken as the reference data set. The effects on NTCP and TCP were evaluated using the Lyman-NTCP model and the Logistic TCP model, respectively. Results: When compared to the predicted NTCP using the reference data set, the treatment plan based on the original CT data-set (UC) yielded an increase of 3.2% and 2.0% in NTCP for the spared parotid gland and the spinal cord. While the treatment plans based on the MVC CT data set NTCP increased by 1.1% and 0.1% for the spared parotid and the spinal cord. In addition, the MVC correction method showed reduced ΔTCP (MVC: 0.6% vs. UC: 1.3%) with respect to that of the reference CT data set. Conclusion: Our results indicate that the presence of dental- metal-artifacts in H&N planning CT data sets has an impact on the estimates of TCP and NTCP. In particular dentalmetal- artifacts lead to an increase in NTCP for the spared parotid and a slight decrease in TCP for TV.",

keywords = "Head and neck, Metal artifacts, NTCP, TCP, Treatment planning",

author = "Yusung Kim and Tom{\'e}, {Wolfgang A.}",

year = "2007",

month = jan,

day = "1",

doi = "10.1007/978-3-540-36841-0_433",

language = "English (US)",

isbn = "9783540368397",

series = "IFMBE Proceedings",

publisher = "Springer Verlag",

number = "1",

pages = "1750--1753",

editor = "Kim, {Sun I.} and Suh, {Tae Suk}",

booktitle = "IFMBE Proceedings",

edition = "1",

note = "10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 ; Conference date: 27-08-2006 Through 01-09-2006",

}

TY - GEN

T1 - The impact of metal artifacts on IMRT dose distributions in TCP and NTCP

AU - Kim, Yusung

AU - Tomé, Wolfgang A.

PY - 2007/1/1

Y1 - 2007/1/1

N2 - Purpose: To investigate the effects of distorted head-and-neck (H&N) IMRT dose distributions (hot and cold spots) on normal tissue complication probability (NTCP) and tumor control probability (TCP) due to dental-metal artifacts. Methods: Five patients’ IMRT treatment plans have been analyzed, employing five different planning image data-sets: (a) uncorrected (UC); (b) homogeneous uncorrected (HUC); (c) sinogram completion corrected (SCC); (d) minimum-valuecorrected (MVC); and (e) streak-artifact-reduction including minimum-value-correction (SAR-MVC), that has been taken as the reference data set. The effects on NTCP and TCP were evaluated using the Lyman-NTCP model and the Logistic TCP model, respectively. Results: When compared to the predicted NTCP using the reference data set, the treatment plan based on the original CT data-set (UC) yielded an increase of 3.2% and 2.0% in NTCP for the spared parotid gland and the spinal cord. While the treatment plans based on the MVC CT data set NTCP increased by 1.1% and 0.1% for the spared parotid and the spinal cord. In addition, the MVC correction method showed reduced ΔTCP (MVC: 0.6% vs. UC: 1.3%) with respect to that of the reference CT data set. Conclusion: Our results indicate that the presence of dental- metal-artifacts in H&N planning CT data sets has an impact on the estimates of TCP and NTCP. In particular dentalmetal- artifacts lead to an increase in NTCP for the spared parotid and a slight decrease in TCP for TV.

AB - Purpose: To investigate the effects of distorted head-and-neck (H&N) IMRT dose distributions (hot and cold spots) on normal tissue complication probability (NTCP) and tumor control probability (TCP) due to dental-metal artifacts. Methods: Five patients’ IMRT treatment plans have been analyzed, employing five different planning image data-sets: (a) uncorrected (UC); (b) homogeneous uncorrected (HUC); (c) sinogram completion corrected (SCC); (d) minimum-valuecorrected (MVC); and (e) streak-artifact-reduction including minimum-value-correction (SAR-MVC), that has been taken as the reference data set. The effects on NTCP and TCP were evaluated using the Lyman-NTCP model and the Logistic TCP model, respectively. Results: When compared to the predicted NTCP using the reference data set, the treatment plan based on the original CT data-set (UC) yielded an increase of 3.2% and 2.0% in NTCP for the spared parotid gland and the spinal cord. While the treatment plans based on the MVC CT data set NTCP increased by 1.1% and 0.1% for the spared parotid and the spinal cord. In addition, the MVC correction method showed reduced ΔTCP (MVC: 0.6% vs. UC: 1.3%) with respect to that of the reference CT data set. Conclusion: Our results indicate that the presence of dental- metal-artifacts in H&N planning CT data sets has an impact on the estimates of TCP and NTCP. In particular dentalmetal- artifacts lead to an increase in NTCP for the spared parotid and a slight decrease in TCP for TV.

KW - Head and neck

KW - Metal artifacts

KW - NTCP

KW - TCP

KW - Treatment planning

UR - http://www.scopus.com/inward/record.url?scp=84958240535&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84958240535&partnerID=8YFLogxK

U2 - 10.1007/978-3-540-36841-0_433

DO - 10.1007/978-3-540-36841-0_433

M3 - Conference contribution

AN - SCOPUS:84958240535

SN - 9783540368397

T3 - IFMBE Proceedings

SP - 1750

EP - 1753

BT - IFMBE Proceedings

A2 - Kim, Sun I.

A2 - Suh, Tae Suk

PB - Springer Verlag

T2 - 10th World Congress on Medical Physics and Biomedical Engineering, WC 2006

Y2 - 27 August 2006 through 1 September 2006

ER -

The impact of metal artifacts on IMRT dose distributions in TCP and NTCP

Abstract

Publication series

Other

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this