The identification of nucleoside triphosphate ends on RNA formed in the RNA polymerase reaction

Umadas Maitra, Abraham Novogrodsky, David Baltimore, Jerard Hurwitz

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

RNA polymerase reactions primed with a variety of different DNA preparations (T2, thymus, denatured thymus and dAT copolymer) lead to the incorporation of 32P from β-γ 32P-labeled ATP into an acid-insoluble form. Evidence has been presented which indicates that the triphosphate group is present at the end of RNA chains.

Original languageEnglish (US)
Pages (from-to)801-811
Number of pages11
JournalBiochemical and Biophysical Research Communications
Volume18
Issue number5-6
StatePublished - Mar 12 1965

Fingerprint

Thymus
DNA-Directed RNA Polymerases
Nucleosides
Thymus Gland
RNA
Copolymers
Adenosine Triphosphate
Acids
DNA
triphosphoric acid

ASJC Scopus subject areas

  • Molecular Biology
  • Biophysics
  • Biochemistry

Cite this

The identification of nucleoside triphosphate ends on RNA formed in the RNA polymerase reaction. / Maitra, Umadas; Novogrodsky, Abraham; Baltimore, David; Hurwitz, Jerard.

In: Biochemical and Biophysical Research Communications, Vol. 18, No. 5-6, 12.03.1965, p. 801-811.

Research output: Contribution to journalArticle

Maitra, Umadas ; Novogrodsky, Abraham ; Baltimore, David ; Hurwitz, Jerard. / The identification of nucleoside triphosphate ends on RNA formed in the RNA polymerase reaction. In: Biochemical and Biophysical Research Communications. 1965 ; Vol. 18, No. 5-6. pp. 801-811.
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