The identification of nucleoside triphosphate ends on RNA formed in the RNA polymerase reaction

Umadas Maitra, Abraham Novogrodsky, David Baltimore, Jerard Hurwitz

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

RNA polymerase reactions primed with a variety of different DNA preparations (T2, thymus, denatured thymus and dAT copolymer) lead to the incorporation of 32P from β-γ 32P-labeled ATP into an acid-insoluble form. Evidence has been presented which indicates that the triphosphate group is present at the end of RNA chains.

Original languageEnglish (US)
Pages (from-to)801-811
Number of pages11
JournalBiochemical and Biophysical Research Communications
Volume18
Issue number5-6
DOIs
StatePublished - Mar 12 1965

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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