The First Report of Bartonella quintana Immune Reconstitution Inflammatory Syndrome Complicated by Jarisch-Herxheimer Reaction

Michelle Dallapiazza; Matthew Jiro Akiyama

doi:10.1177/2325957417702484

The First Report of Bartonella quintana Immune Reconstitution Inflammatory Syndrome Complicated by Jarisch-Herxheimer Reaction

Michelle Dallapiazza, Matthew Jiro Akiyama

Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Bacillary angiomatosis (BA) is a rare complication of human immune deficiency virus (HIV) infection in the post-antiretroviral therapy (ART) era, and few cases of BA-associated immune reconstitution inflammatory syndrome (IRIS) have been described. We report the case of a 50-year-old man who presented with mass lesions involving the skin, subcutaneous tissues, muscle, and bone. The diagnosis of Bartonella quintana BA was confirmed by serum polymerase chain reaction. The patient's treatment course was complicated by both IRIS and Jarisch-Herxheimer reaction. The case had a favorable outcome with supportive care and continuation of ART and doxycycline.

Original language	English (US)
Pages (from-to)	321-323
Number of pages	3
Journal	Journal of the International Association of Providers of AIDS Care
Volume	16
Issue number	4
DOIs	https://doi.org/10.1177/2325957417702484
State	Published - Jul 1 2017

Keywords

Bartonella quintana
HIV
Jarisch-Herxheimer reaction
bacillary angiomatosis
immune reconstitution inflammatory syndrome

ASJC Scopus subject areas

Immunology
Dermatology
Infectious Diseases

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10.1177/2325957417702484

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title = "The First Report of Bartonella quintana Immune Reconstitution Inflammatory Syndrome Complicated by Jarisch-Herxheimer Reaction",

abstract = "Bacillary angiomatosis (BA) is a rare complication of human immune deficiency virus (HIV) infection in the post-antiretroviral therapy (ART) era, and few cases of BA-associated immune reconstitution inflammatory syndrome (IRIS) have been described. We report the case of a 50-year-old man who presented with mass lesions involving the skin, subcutaneous tissues, muscle, and bone. The diagnosis of Bartonella quintana BA was confirmed by serum polymerase chain reaction. The patient's treatment course was complicated by both IRIS and Jarisch-Herxheimer reaction. The case had a favorable outcome with supportive care and continuation of ART and doxycycline.",

keywords = "Bartonella quintana, HIV, Jarisch-Herxheimer reaction, bacillary angiomatosis, immune reconstitution inflammatory syndrome",

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AU - Akiyama, Matthew Jiro

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N2 - Bacillary angiomatosis (BA) is a rare complication of human immune deficiency virus (HIV) infection in the post-antiretroviral therapy (ART) era, and few cases of BA-associated immune reconstitution inflammatory syndrome (IRIS) have been described. We report the case of a 50-year-old man who presented with mass lesions involving the skin, subcutaneous tissues, muscle, and bone. The diagnosis of Bartonella quintana BA was confirmed by serum polymerase chain reaction. The patient's treatment course was complicated by both IRIS and Jarisch-Herxheimer reaction. The case had a favorable outcome with supportive care and continuation of ART and doxycycline.

AB - Bacillary angiomatosis (BA) is a rare complication of human immune deficiency virus (HIV) infection in the post-antiretroviral therapy (ART) era, and few cases of BA-associated immune reconstitution inflammatory syndrome (IRIS) have been described. We report the case of a 50-year-old man who presented with mass lesions involving the skin, subcutaneous tissues, muscle, and bone. The diagnosis of Bartonella quintana BA was confirmed by serum polymerase chain reaction. The patient's treatment course was complicated by both IRIS and Jarisch-Herxheimer reaction. The case had a favorable outcome with supportive care and continuation of ART and doxycycline.

KW - Bartonella quintana

KW - HIV

KW - Jarisch-Herxheimer reaction

KW - bacillary angiomatosis

KW - immune reconstitution inflammatory syndrome

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The First Report of Bartonella quintana Immune Reconstitution Inflammatory Syndrome Complicated by Jarisch-Herxheimer Reaction

Abstract

Keywords

ASJC Scopus subject areas

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