The fine structure of phosphotungstic acid stained neuropathologic tissue

Asao Hirano, Herbert M. Dembitzer, H. M. Zimmerman

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The ethanolic phosphotungstic acid technique of Bloom and Aghajanian has been applied to formalin-fixed neuropathological specimens. The staining reactions of various normal organelles were studied as well as a number of pathological alterations including Alzheimer neurofibrillary tangles, eosinophilic rod-like structures, corpora amylacea, lamellar bodies and honeycomb-like structures in the axoplasm.

Original languageEnglish (US)
Pages (from-to)265-272
Number of pages8
JournalActa neuropathologica
Issue number3
StatePublished - Sep 1 1973


  • Alzheimer Neurofibrillary Tangles
  • Electron Microscope
  • Eosinophilic Rod-like Structures
  • Phosphotungstic Acid

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology
  • Cellular and Molecular Neuroscience


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