The fine structure of astroblastoma

T. Kubota, A. Hirano, K. Sato, S. Yamamoto

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

An astroblastoma in the cerebrum was investigated with the electron microscope. A distinctive feature of the tumor was the radial arrangement of astrocytic cells around the blood vessels. The blood vessels in the tumor commonly exhibited fenestrated endothelial cells. The endothelium was generally surrounded by lamellated basal laminae that were compactly invested in the neoplastic cells. The most remarkable feature of the tumor cells was the most frequent presence of coated vesicles. The cytoplasm of some tumor cells was filled by delicate glial fibrils and microtubules, whereas that of others contained a moderate amount of rough-surfaced endoplasmic reticulum, free ribosomes, and mitochondria, but only scanty glial fibrils and microtubules. The former usually possessed long, thin cell processes, whereas the latter had poor development of cell processes and commonly showed multiple or giant nuclei containing several nuclear bodies and prominent nucleoli. In summary, this ultrastructural study of astroblastoma revealed the coexistence of varied maturity astrocytic cells and their compact arrangement around fenestrated blood vessels.

Original languageEnglish (US)
Pages (from-to)745-750
Number of pages6
JournalCancer
Volume55
Issue number4
StatePublished - 1985

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Neuroepithelial Neoplasms
Microtubules
Neuroglia
Blood Vessels
Vascular Tissue Neoplasms
Coated Vesicles
Neoplasms
Rough Endoplasmic Reticulum
Cerebrum
Ribosomes
Basement Membrane
Endothelium
Mitochondria
Cytoplasm
Endothelial Cells
Electrons

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Kubota, T., Hirano, A., Sato, K., & Yamamoto, S. (1985). The fine structure of astroblastoma. Cancer, 55(4), 745-750.

The fine structure of astroblastoma. / Kubota, T.; Hirano, A.; Sato, K.; Yamamoto, S.

In: Cancer, Vol. 55, No. 4, 1985, p. 745-750.

Research output: Contribution to journalArticle

Kubota, T, Hirano, A, Sato, K & Yamamoto, S 1985, 'The fine structure of astroblastoma', Cancer, vol. 55, no. 4, pp. 745-750.
Kubota T, Hirano A, Sato K, Yamamoto S. The fine structure of astroblastoma. Cancer. 1985;55(4):745-750.
Kubota, T. ; Hirano, A. ; Sato, K. ; Yamamoto, S. / The fine structure of astroblastoma. In: Cancer. 1985 ; Vol. 55, No. 4. pp. 745-750.
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