The evolving role of glycoprotein (GP) IIb/IIIa receptor blockade during percutaneous coronary intervention of saphenous vein bypass grafts

David J. D'Agate, Snehal R. Patel, John T. Coppola, John A. Ambrose

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

PCI has improved the treatment of coronary artery disease. However, unlike native coronary arteries, progress in the percutaneous intervention of SVBG has been disappointing, often complicated by distal embolization of atherothrombotic debris and resulting in high periprocedural morbidity. SVBG interventions have an increased incidence of major adverse clinical events compared to native coronary interventions, with approximately 20% of vein graft interventions complicated by myocardial infarction or no-reflow phenomenon. We review the morphological features complicating saphenous vein graft disease, the current literature regarding GP receptor blockade in vein graft interventions and potential future therapies.

Original languageEnglish (US)
Pages (from-to)500-503
Number of pages4
JournalJournal of Invasive Cardiology
Volume16
Issue number9
StatePublished - Sep 2004
Externally publishedYes

Fingerprint

Platelet Glycoprotein GPIIb-IIIa Complex
Saphenous Vein
Percutaneous Coronary Intervention
Transplants
Veins
No-Reflow Phenomenon
Coronary Artery Disease
Coronary Vessels
Glycoproteins
Myocardial Infarction
Morbidity
Incidence
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

The evolving role of glycoprotein (GP) IIb/IIIa receptor blockade during percutaneous coronary intervention of saphenous vein bypass grafts. / D'Agate, David J.; Patel, Snehal R.; Coppola, John T.; Ambrose, John A.

In: Journal of Invasive Cardiology, Vol. 16, No. 9, 09.2004, p. 500-503.

Research output: Contribution to journalArticle

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