The evaluation of ciliary function: Electron versus light microscopy

Stephen B. Kupferberg, John P. Bent, Edward S. Porubsky

Research output: Contribution to journalArticle

5 Scopus citations


Diagnosing Primary Ciliary Dyskinesia can often be difficult. Physical findings suggest the disease, but definitive diagnosis should be made with a ciliary biopsy. Twenty biopsies were obtained from 16 patients and all underwent both light and electron microscopic examination. In 8/20 (40%) there was a discrepancy between the different imaging techniques. Therefore, light microscopy should be used to assess adequacy of biopsy and motion of the cilia alone with electron microscopy to examine ultrastructure.

Original languageEnglish (US)
Pages (from-to)199-201
Number of pages3
JournalAmerican Journal of Rhinology
Issue number3
Publication statusPublished - Jan 1 1998
Externally publishedYes


ASJC Scopus subject areas

  • Otorhinolaryngology

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