TY - JOUR
T1 - The evaluation of ciliary function
T2 - Electron versus light microscopy
AU - Kupferberg, Stephen B.
AU - Bent, John P.
AU - Porubsky, Edward S.
PY - 1998
Y1 - 1998
N2 - Diagnosing Primary Ciliary Dyskinesia can often be difficult. Physical findings suggest the disease, but definitive diagnosis should be made with a ciliary biopsy. Twenty biopsies were obtained from 16 patients and all underwent both light and electron microscopic examination. In 8/20 (40%) there was a discrepancy between the different imaging techniques. Therefore, light microscopy should be used to assess adequacy of biopsy and motion of the cilia alone with electron microscopy to examine ultrastructure.
AB - Diagnosing Primary Ciliary Dyskinesia can often be difficult. Physical findings suggest the disease, but definitive diagnosis should be made with a ciliary biopsy. Twenty biopsies were obtained from 16 patients and all underwent both light and electron microscopic examination. In 8/20 (40%) there was a discrepancy between the different imaging techniques. Therefore, light microscopy should be used to assess adequacy of biopsy and motion of the cilia alone with electron microscopy to examine ultrastructure.
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U2 - 10.2500/105065898781390172
DO - 10.2500/105065898781390172
M3 - Article
C2 - 9653478
AN - SCOPUS:0032059780
SN - 1050-6586
VL - 12
SP - 199
EP - 201
JO - American Journal of Rhinology
JF - American Journal of Rhinology
IS - 3
ER -