The Essence of Aging

Jan Vijg, Brian K. Kennedy

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The idea that aging is a purposeful, programmed series of events is intuitively appealing based on its many conserved aspects and the demonstrated feasibility of modifying life span by manipulating single genes or pathways. Yet, the case for a nonadaptive basis of aging is strong and now all but generally accepted in the field. Here, we briefly review why the case for programmed aging is weak, with a focus on the lack of possible evolutionary beneficial effects.

Original languageEnglish (US)
JournalGerontology
DOIs
StateAccepted/In press - Sep 22 2015

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Keywords

  • Adaptive theories
  • Antagonistic pleiotropy
  • Dietary restriction
  • Programmed aging

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology

Cite this

The Essence of Aging. / Vijg, Jan; Kennedy, Brian K.

In: Gerontology, 22.09.2015.

Research output: Contribution to journalArticle

Vijg, Jan ; Kennedy, Brian K. / The Essence of Aging. In: Gerontology. 2015.
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