The emergence of networks in human genome epidemiology: Challenges and opportunities

Daniela Seminara, Muin J. Khoury, Thomas R. O'brien, Teri Manolio, Marta Gwinn, Julian Little, Julian P T Higgins, Jonine L. Bernstein, Paolo Boffetta, Melissa L. Bondy, Molly S. Bray, Paul E. Brenchley, Patricia A. Buffler, Juan Pablo Casas, Anand P. Chokkalingam, John Danesh, George Davey Smith, Siobhan M. Dolan, Ross Duncan, Nelleke A. GruisMia Hashibe, David J. Hunter, Marjo Riitta Jarvelin, Beatrice Malmer, Demetrius M. Maraganore, Julia A. Newton-Bishop, Elio Riboli, Georgia Salanti, Emanuela Taioli, Nic Timpson, André G. Uitterlinden, Paolo Vineis, Nick Wareham, Deborah M. Winn, Ron Zimmern, John P A Ioannidis

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The Human Genome Epidemiology Network (HuGENet) recently launched a global network of consortia working on human genome epidemiology. This Network of Investigator Networks aims to create a resource to share information, offer methodologic support, generate inclusive overviews of studies conducted in specific fields, and to facilitate rapid confirmation of findings. In October 2005, HuGENet brought together representatives from established and emerging networks in order to share their experiences at a workshop in Cambridge, United Kingdom. In advance of the meeting, a qualitative questionnaire was distributed to workshop participants. The questionnaire elicited information on experiences and practices in building and maintaining consortia. This chapter reports on the numerous challenges and their possible solutions as identified by the workshop participants, as well as new opportunities offered by the network approach to genetic and genomic epidemiology.

Original languageEnglish (US)
Title of host publicationHuman Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition
PublisherOxford University Press
ISBN (Print)9780199776023, 9780195398441
DOIs
StatePublished - May 1 2010

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Human Genome
Epidemiology
Education
Molecular Epidemiology
Research Personnel
Surveys and Questionnaires

Keywords

  • Genetic epidemiology
  • Hugenet
  • Human genome epidemiology
  • Investigator networks

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Seminara, D., Khoury, M. J., O'brien, T. R., Manolio, T., Gwinn, M., Little, J., ... Ioannidis, J. P. A. (2010). The emergence of networks in human genome epidemiology: Challenges and opportunities. In Human Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition Oxford University Press. https://doi.org/10.1093/acprof:oso/9780195398441.003.0007

The emergence of networks in human genome epidemiology : Challenges and opportunities. / Seminara, Daniela; Khoury, Muin J.; O'brien, Thomas R.; Manolio, Teri; Gwinn, Marta; Little, Julian; Higgins, Julian P T; Bernstein, Jonine L.; Boffetta, Paolo; Bondy, Melissa L.; Bray, Molly S.; Brenchley, Paul E.; Buffler, Patricia A.; Casas, Juan Pablo; Chokkalingam, Anand P.; Danesh, John; Smith, George Davey; Dolan, Siobhan M.; Duncan, Ross; Gruis, Nelleke A.; Hashibe, Mia; Hunter, David J.; Jarvelin, Marjo Riitta; Malmer, Beatrice; Maraganore, Demetrius M.; Newton-Bishop, Julia A.; Riboli, Elio; Salanti, Georgia; Taioli, Emanuela; Timpson, Nic; Uitterlinden, André G.; Vineis, Paolo; Wareham, Nick; Winn, Deborah M.; Zimmern, Ron; Ioannidis, John P A.

Human Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition. Oxford University Press, 2010.

Research output: Chapter in Book/Report/Conference proceedingChapter

Seminara, D, Khoury, MJ, O'brien, TR, Manolio, T, Gwinn, M, Little, J, Higgins, JPT, Bernstein, JL, Boffetta, P, Bondy, ML, Bray, MS, Brenchley, PE, Buffler, PA, Casas, JP, Chokkalingam, AP, Danesh, J, Smith, GD, Dolan, SM, Duncan, R, Gruis, NA, Hashibe, M, Hunter, DJ, Jarvelin, MR, Malmer, B, Maraganore, DM, Newton-Bishop, JA, Riboli, E, Salanti, G, Taioli, E, Timpson, N, Uitterlinden, AG, Vineis, P, Wareham, N, Winn, DM, Zimmern, R & Ioannidis, JPA 2010, The emergence of networks in human genome epidemiology: Challenges and opportunities. in Human Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition. Oxford University Press. https://doi.org/10.1093/acprof:oso/9780195398441.003.0007
Seminara D, Khoury MJ, O'brien TR, Manolio T, Gwinn M, Little J et al. The emergence of networks in human genome epidemiology: Challenges and opportunities. In Human Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition. Oxford University Press. 2010 https://doi.org/10.1093/acprof:oso/9780195398441.003.0007
Seminara, Daniela ; Khoury, Muin J. ; O'brien, Thomas R. ; Manolio, Teri ; Gwinn, Marta ; Little, Julian ; Higgins, Julian P T ; Bernstein, Jonine L. ; Boffetta, Paolo ; Bondy, Melissa L. ; Bray, Molly S. ; Brenchley, Paul E. ; Buffler, Patricia A. ; Casas, Juan Pablo ; Chokkalingam, Anand P. ; Danesh, John ; Smith, George Davey ; Dolan, Siobhan M. ; Duncan, Ross ; Gruis, Nelleke A. ; Hashibe, Mia ; Hunter, David J. ; Jarvelin, Marjo Riitta ; Malmer, Beatrice ; Maraganore, Demetrius M. ; Newton-Bishop, Julia A. ; Riboli, Elio ; Salanti, Georgia ; Taioli, Emanuela ; Timpson, Nic ; Uitterlinden, André G. ; Vineis, Paolo ; Wareham, Nick ; Winn, Deborah M. ; Zimmern, Ron ; Ioannidis, John P A. / The emergence of networks in human genome epidemiology : Challenges and opportunities. Human Genome Epidemiology: Building the Evidence for Using Genetic Information to Improve Health and Prevent Disease: Second Edition. Oxford University Press, 2010.
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